Magnetic dispersive solid-phase extraction based on a novel adsorbent for the detection of triazole pesticide residues in honey by HPLC-MS/MS

Abstract

A novel Fe 3 O 4 @MDN magnetic nanomaterial was successfully developed as a magnetic dispersive solidphase extraction adsorbent for the determination of triazole pesticide residuals in honey samples by high performance liquid chromatography coupled with triple quadrupole mass spectrometry (HPLC-MS/MS). The macromolecular structure named MDN was coated on the surface of a copolymer synthesized with silyl reagents methacrylic acid-3-(trimethoxysilyl) propyl ester (MPS) and tetraethyl orthosilicate (TEOS) based on ferriferrous oxide (Fe 3 O 4 ), whose characteristics were confirmed by a scanning electron microscope (SEM). The proposed magnetic dispersive solid-phase extraction (MDSPE) method provided a rapid, environmentally friendly and magnetic stuff recyclable approach for the triazole pesticide analysis. By means of optimal conditions, the recoveries of 15 triazoles (spiked at 20 mg kg À1 ) ranged from 90.5 to 105.9%. The method showed good linearity, sensitivity in the range of mg per kilogram and repeatability (relative standard deviation below 6.8%, n ¼ 5). The proposed method was confirmed to be a simple, rapid and efficient method for the analysis of triazole pesticide residuals in honey samples.

Detection of 13 mycotoxins in feed using modified QuEChERS with dispersive magnetic materials and UHPLC–MS/MS

“…Magnetic sorbent MDN@Fe 3 O 4 , which contained the functional N-vinylpyrrolidone group and could adsorb hydrophobic and hydrophilic interferences, was prepared and characterized using our previously established method [23]. Magnetic sorbent PSA@Fe 3 O 4 that contained primary secondary amine could adsorb acidic interferences and was prepared and characterized using the method in our laboratory [24].…”

Preparation of a magnetic multiwalled carbon nanotube@polydopamine/zeolitic imidazolate framework-8 composite for magnetic solid-phase extraction of triazole fungicides from environmental water samples

“…Therefore, development of effective and sensitive techniques for determination of triazole fungicides in environmental water is vital. 4,5 Sample preparation is the key procedure for analysis of pesticide residues. In recent years, various techniques have been developed to determine triazole fungicides in aqueous solutions, such as solid-phase extraction (SPE), solid-phase microextraction, and stir-bar sorptive extraction.…”

Microwave‐assisted‐demulsification dispersive liquid–liquid microextraction for the determination of triazole fungicides in water by gas chromatography with mass spectrometry

“…Up to now, HPLC [8][9][10] and GC [11][12][13][14][15] have been the most widely used analytical techniques in separation and quantification of triazole pesticide residues in different samples. Besides, sample pretreatment technology plays a key role in the pesticide residue analysis.…”

“…in 2006 . Recently, a variety of improved DLLME methods have been developed for determination of triazole pesticide residues, such as air‐assisted dispersive liquid–liquid microextraction (AA‐DLLME) , coupling stir bar sorptive extraction with dispersive liquid–liquid microextraction , DLLME based on solidification of floating organic droplet , vortex‐assisted ionic liquid dispersive liquid–liquid microextraction , ultrasound assisted salting‐out homogenous liquid–liquid microextraction , homogenous liquid–liquid extraction based on a narrow‐bore tube , and effervescence‐assisted dispersive liquid–liquid microextraction . However, in most traditional DLLME, the extractant was usually a water‐insoluble organic solvent with a density greater than that of water, and simple phase separation was carried out by centrifugation.…”