Magnetic biosensors for genetic screening of cystic fibrosis

Lagae, Liesbet; Wirix-Speetjens, Roel; Liu, C.-X.; Laureyn, Wim; Borghs, Gustaaf; Harvey, Steven P.; Galvin, Paul; Ferreira, Hugo Alexandre; Graham, Daniel L.; Freitas, P. P.; Clarke, Luka A.; Amaral, Margarida D.

doi:10.1049/ip-cds:20050022

Cited by 29 publications

(10 citation statements)

References 15 publications

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“…Mainly for this purpose, magnetic particles are available commercially. In addition, magnetic actuation techniques for particle transportation Lagae et al, 2005;Wirix-Speetjens et al, 2005) and magnetic washing (Fukumoto et al, 2005) can also be integrated on-chip.…”

Section: Introductionmentioning

confidence: 98%

An integrated and sensitive detection platform for magneto-resistive biosensors

Boer

Kahlman

Jansén

et al. 2007

Biosensors and Bioelectronics

111

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Section: Introductionmentioning

confidence: 98%

An integrated and sensitive detection platform for magneto-resistive biosensors

Boer

Kahlman

Jansén

et al. 2007

Biosensors and Bioelectronics

111

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“…(3), V m was obtained from the data sheet given by Bangs Lab inc. and Dv was calculated from the literature (Lagae et al 2005). Finally, rB 2 as determined by measuring magnetic fields with a gauss meter (LakeShore 475 DSP) and calculating based on the inverse square law.…”

Section: Theorymentioning

confidence: 99%

Separation of apoptotic cells using a microfluidic device

Son

Kim

et al. 2007

Biotechnol Lett

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A highly sensitive microfluidic device has been developed to separate apoptotic cells. Apoptotic Jurkat cells were selectively labeled with magnetic beads (0.8 microm diam) using the C2A protein which recognizes phosphatidylserine. The cell mixture was flowed through a microfluidic channel and apoptotic cells were separated by a 0.3 T permanent magnet. Separations using our device showed 96% agreement with those of a commercial flow cytometer, indicating our device can be used to sort apoptotic cells in a miniaturized system.

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“…Magnetic biosensors can provide more accurate results than florescent; some magnetic biosensors have demonstrated being able to detect single magnetic labels [2], [8]- [10]. Magnetic biosensors can produce faster readouts which is essential when dealing with harmful pathogens, have the possibility of being smaller and more portable, as well as being cheaper to produce due to simplicity or using current large scale fabrication techniques [5], [11]. It has been demonstrated that the shape of the magnetic nanoelements predominately determines the distribution and strength of the external demagnetizing field formed from the nanoelements [12], [13].…”

Section: Introductionmentioning

confidence: 98%

Shape Effect of Magnetic Nanoelements as Biomolecular Labels for Magnetic Biosensors

Bowerbank

Ding

et al. 2012

IEEE Trans. Magn.

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Four magnetic nanoelements of different shapes were investigated at varying distances from a permalloy nanowire to see how the shape of the nanoelements affected the resultant demagnetizing field from the nanoelements onto the nanowire. All results were simulated using micromagnetic simulations by Object Oriented Micromagnetic Framework (OOMMF). It is shown that the square nanoelements performed the best and that the shape anisotropy has an important role in determining the external demagnetizing field for nanoelements.

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Magnetic biosensors for genetic screening of cystic fibrosis

Cited by 29 publications

References 15 publications

An integrated and sensitive detection platform for magneto-resistive biosensors

An integrated and sensitive detection platform for magneto-resistive biosensors

Separation of apoptotic cells using a microfluidic device

Shape Effect of Magnetic Nanoelements as Biomolecular Labels for Magnetic Biosensors

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