Magnetic and spectroscopic studies on N-(picolinamido)salicylaldimine complexes of some bivalent 3d metal ions

Aggarwal, R. C.; Singh, Nisha; Singh, Vikram

doi:10.1021/ic50223a012

Cited by 108 publications

(39 citation statements)

References 4 publications

(6 reference statements)

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“…In the spectra of the Cu(II) complexes (Table III), these proton signals appeared much more downfield, as expected, due to increased 28 29 conjugation during coordination [14][15][16][17][18] (64-82 %); +++% [18][19][20][21][22] (82-100 %). Percent inhibition values are relative to inhibition zone (22 mm) of the most active compound with 100 % inhibition.…”

Section: Nmr Spectrasupporting

confidence: 65%

“…The appearance of weak, low 25 frequency new bands at~360 and --455 cm" were assigned to metal-sulfur v(M-S) in the thienyl and metal-oxygen v(M-O) in the furanyl ligands. These bands were only observable in the spectra of the metal complexes and not in the spectra of their Schiff bases which in turn confmned the participation of the 22,26 heteroatoms X (S or O) in the coordination. These observations, in turn, suggested a square planar geometry for the Cu(II) complexes (Fig.…”

Section: Introductionmentioning

confidence: 96%

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Copper (II) Acylhydrazinates. Their Synthesis and Characterization

Chohan

Farooq

Supuran³

2000

Metal-Based Drugs

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Section: Nmr Spectrasupporting

confidence: 65%

Section: Introductionmentioning

confidence: 96%

Copper (II) Acylhydrazinates. Their Synthesis and Characterization

Chohan

Farooq

Supuran³

2000

Metal-Based Drugs

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“…Based on these normal magnetic moment values, there seems to be no exchange interaction between the copper(II) ions in the solid state of these copper(II) chelates. This fact finds support from the ESR spectral data which give G values in the range 5.3825 -6.9749 > 4.0 [37]. The EPR spectra of the inspected copper(II) complexes in the polycrystalline state at 298 K were recorded in the Xband region, using 100 KHz field modulation and the g factors; g || and g ⊥ values were quoted from the spectra relative to the standard g-marker DPPH ( g = 2.0023).…”

Section: Ir Spectral Studies:-supporting

confidence: 61%

Synthesis and Characterization of N3s2 Donors Macrocyclic Copper(ii) Complexes. Catechol Oxidase and Phenoxazinone Synthase Biomimetic Catalytic Activity.

Ramadan¹,

Shaban²,

Khalil³

et al. 2017

IJAR

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A new series of hexa-, and five-coordinated copper(II) complexes, having the molecular formulae of [CuLX]X H 2 O, 1, 2, 3 (X = Cl¯, Br¯, NO 3¯) and [CuL]X 2 nH 2 O, 4, 5 (X= AcO¯ and ClO 4¯) respectively and L is pentadentate pyridine based ligand have been synthesized. Structural characterization of these newly synthesized compounds was achieved by several physicochemical methods including elemental and thermal analysis (TGA and DTG), electrical molar conductance, magnetic moment measurements and spectral investigations such as IR, UV-Vis and ESR. The spectral and magnetic measurements in addition to the electrolytic conductance results demonstrated the octahedral and square-pyramidal stereochemistries for the hexa, and five coordinated copper(II) chelates respectively. Catechol oxidase and phenoxazinone synthase biomimetic catalytic activity of the inspected copper(II) chelates was studied and the results obtained indicated that, the catalytic reactivity is markedly depends on the structural properties of these newly synthesized copper(II) complexes. …………………………………………………………………………………………………….... Introduction:-Functional models of the metalloenzymes that activate molecular oxygen possess great potential as catalyst for specific oxidation reactions and as guides for the development of efficient small molecule catalysts [1]. Since, the oxidation of organic substrates with molecular oxygen under mild conditions is of great interest for industrial [2] and synthetic processes both from an economical and environmental [3] point of view, most of the focus of ongoing biomimetic and bioinspired synthetic approaches is on reproducing some structural and/or functional feature of the title enzymes. The synthesis and reactivity studies of transition metal complexes, as functional model compounds for metalloenzymes with oxidase activity, are of particular interest for the development of bioinspired catalysts for oxidation reactions.The potential role played by copper ions in the active sites of a large number of metalloproteins has stimulated efforts to design and characterize copper complexes as models for providing better understanding of biological systems and for assisting in the development of new homogeneous catalysts for selective oxidation. Particularly, the

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“…ESR Spectra 35,36) Antibacterial Activity Antibacterial activities of Co(II), Ni(II), Cu(II) and Pd(II) complexes were studied along with the metal salts (cobalt(II) acetate, nickel(II) acetate, copper(II) acetate, and palladium(II) chloride), metal free ligands and two existing antibacterial drugs viz., streptomycin and ampicillin. Preliminary screening for all the metal salts, metal free ligands and complexes were performed at the fixed concentration of 1000 mg/ml.…”

Section: -27)mentioning

confidence: 99%

Synthesis, Characterization and Biological Evaluation of Mononuclear Co(II), Ni(II), Cu(II) and Pd(II) Complexes with New N2O2 Schiff Base Ligands

Budige

Puchakayala

Kongara

et al. 2011

CHEMICAL & PHARMACEUTICAL BULLETIN

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Schiff bases have a variety of applications in biological, clinical, and pharmacological areas. The synthesis and application of Schiff bases and their coordination compounds have been highly considered in inorganic, organic and biological fields, since their structural properties similar to some of the biological systems.1-6) Additionally, tetradentate Schiff bases composed of N 2 O 2 donor atoms set have been recognized as a kind of important chelating ligands for designing medicinally and catalytically useful metal complexes. [7][8][9] The flexible coordination behavior of these types of chelating ligands could also be useful to generate interesting dimeric and polymeric structures as synthones for supramolecular chemistry. 10,11) Usually, the N, O donor heterodentate Schiff bases can be derived by condensing the aldehydes/ketones with various amines or amino acids. 12,13) N 2 O 2 Schiff base ligands derived from salicylald ehyde and diamine have been known. 14,15) Dialdehydes and diketones with amines and amino acids have also been utilized to obtain a variety of N 2 O 2 Schiff base ligands. 16)Amino acids plays an important role in many physiological activities of the human body and also helpful in understanding biological functions of macromolecules such as proteins. 17) In particular, tryptophan (Trp)/histidine (His) analogues as promising candidates for novel antimicrobial therapeutics. In the recent years, a series of synthetic peptide analogues based on Trp-His and His-Arg (antimicrobial peptides) structural frameworks have been prepared and found to be active against several Gram-positive and Gram-negative bacterial strains as well as against fungal strains.18) Furthermore, it is well known that the human body contains essential metaloelements which play important roles and interact with many biological molecules to fully understand the physiological functions by studying their chemistry coordination and behavior. 17,18) In the present studies we have introduced an azomethine (Schiff base) linkage to tryptophan/histidine, which may permit a variety in their coordination behaviour and complexation role.In previous studies, we have described the synthesis, catalytic and biological applications of Schiff bases and their metal complexes derived from o-phthalaldehyde (OPA) with various amines. [19][20][21][22][23][24][25][26][27] In this respect, we have also developed some useful macrocyclic Schiff bases and their metal complexes. Results from these studies have also shown that complexation of metals with Schiff base ligands serves to improve their antimicrobial activity. There are few other research groups also reported the importance of Schiff base chemistry of the combination of o-phthalaldehyde with amines.28,29) However, a careful literature survey reveals that Schiff bases from the combination of amino acids and o-phthalaldehyde and their coordination behavior towards the transition elements have yet not been studied. The combination of dialdehyde i.e. o-phthalaldehyde and aminoacids is expected to ...

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Magnetic and spectroscopic studies on N-(picolinamido)salicylaldimine complexes of some bivalent 3d metal ions

Cited by 108 publications

References 4 publications

Copper (II) Acylhydrazinates. Their Synthesis and Characterization

Copper (II) Acylhydrazinates. Their Synthesis and Characterization

Synthesis and Characterization of N3s2 Donors Macrocyclic Copper(ii) Complexes. Catechol Oxidase and Phenoxazinone Synthase Biomimetic Catalytic Activity.

Synthesis, Characterization and Biological Evaluation of Mononuclear Co(II), Ni(II), Cu(II) and Pd(II) Complexes with New N2O2 Schiff Base Ligands

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