Magnesium

Volpe, Stella L.

doi:10.1002/9781119946045.ch30

Cited by 22 publications

(12 citation statements)

References 95 publications

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“…This finding is similar to other US population studies. 7 Magnesium excretion increases while absorption decreases with age 32 because of various chronic diseases and decreased intake of foods high in magnesium. Compared with imipramine, magnesium supplementation was effective in treating depression in older adults with hypomagnesemia and type 2 diabetes in a randomized controlled trial.…”

Section: Discussionmentioning

confidence: 99%

Magnesium Intake and Depression in Adults

Tarleton

Littenberg

2015

The Journal of the American Board of Family Medicine

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Background: Depression is a common and often disabling disorder. Magnesium supplementation has been linked to improvement in depressive symptoms, but consensus on the relationship between magnesium and depression has not been reached.Methods: The purpose of this study was to test the existence of an association between dietary magnesium intake and depression in the adult US population. A cross-sectional, population-based data set (National Health and Nutrition Examination Survey) was used to explore the relationship of magnesium intake and depression in 8894 US adults (mean age, 46.1 years; 47.4% men) from 2007 to 2010. Using logistic regression to model the relationship between the presence of depression (Patient Health Questionnaire score >5) and low magnesium intake (<184 mg/day), we examined the risk ratio (RR) of magnesium intake and its 95% confidence interval.Results: After adjusting for all potential confounders, the strength of the association of very low magnesium intake with depression was statistically significant (RR ‫؍‬ 1.16; 95% CI, 1.06 -1.30). Adjusting for all other covariates, low magnesium intake was associated with depression in subjects younger than age 65 (RR, 1.22; 95% CI, 1.06 -1.40; P ‫؍‬ .007) but seemed to be protective in seniors (RR, 0.75; 95% CI, 0.56 -0.98; P ‫؍‬ .032).Conclusions: We found a significant association between very low magnesium intake and depression, especially in younger adults. The finding of the potential protective effect of low magnesium intake in older adults is surprising and warrants further investigation. (J Am Board Fam Med 2015;28:249 -256.)

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Section: Discussionmentioning

confidence: 99%

Magnesium Intake and Depression in Adults

Tarleton

Littenberg

2015

The Journal of the American Board of Family Medicine

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“…Furthermore, it is difficult to diagnose magnesium deficiency as total body levels are difficult to assess given its primarily intracellular and intraosseous nature. In other words, serum testing is inadequate to determine the magnesium status of the body as only about 1% of magnesium is found in plasma and red blood cells [ 110 , 112 ].…”

Section: Requirements For a Healthy Pregnancy And Infantmentioning

confidence: 99%

Preconception Care: A New Standard of Care within Maternal Health Services

Genuis

Genuis²

2016

BioMed Research International

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Emerging research suggests that much pediatric affliction has origins in the vulnerable phase of fetal development. Prenatal factors including deficiency of various nutrients and exposure to assorted toxicants are major etiological determinants of myriad obstetrical complications, pediatric chronic diseases, and perhaps some genetic mutations. With recent recognition that modifiable environmental determinants, rather than genetic predestination, are the etiological source of most chronic illness, modification of environmental factors prior to conception offers the possibility of precluding various mental and physical health conditions. Environmental and lifestyle modification through informed patient choice is possible but evidence confirms that, with little to no training in clinical nutrition, toxicology, or environmental exposures, most clinicians are ill-equipped to counsel patients about this important area. With the totality of available scientific evidence that now exists on the potential to modify disease-causing gestational determinants, failure to take necessary precautionary action may render members of the medical community collectively and individually culpable for preventable illness in children. We advocate for environmental health education of maternity health professionals and the widespread adoption and implementation of preconception care. This will necessitate the translation of emerging knowledge from recent research literature, to health professionals, to reproductive-aged women, and to society at large.

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“…The adult body contains approximately 24 g of magnesium, with 50% to 60% present in bones with the rest being contained in soft tissues. Serum magnesium represents less than 1% of total body magnesium 2. In industrialised western countries, a low intake of magnesium often predisposes to a high prevalence of magnesium deficiency increasing the risk of cardiovascular events and cardiovascular death 3.…”

Section: Introductionmentioning

confidence: 99%