Macronutrient Absorption Characteristics in Humans With Short Bowel Syndrome and Jejunocolonic Anastomosis: Starch Is the Most Important Carbohydrate Substrate, Although Pectin Supplementation May Modestly Enhance Short Chain Fatty Acid Production and Fluid Absorption

Atia, Antwan; Girard-Pipau, F.; Hébuterne, Xavier; Spies, William G.; Guardiola, Antonella; Ahn, Chul; Fryer, Jacqueline F.; Xue, Fengtian; Rammohan, Meena; Sumague, Mariquita; Englyst, Klaus; Buchman, Alan L.

doi:10.1177/0148607110378410

Cited by 53 publications

(32 citation statements)

References 63 publications

(55 reference statements)

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“…However, a pectin supplement did not increase macronutrient or energy absorption (1768 vs. 1477 kcal/day, p = 0.15); faecal wet weight (1582 vs 1689 g/day, p = 1.00) and urine production (1615 vs. 1610 ml/d, p = 1.00) remained constant [22]. SBS patients with a colon in continuity report beneficial effects of ispaghula husk and calcium on stool viscosity and consistency, which may ameliorate the sensation of urgency [23].…”

Section: Oral Dietmentioning

confidence: 87%

The non-surgical treatment of adult patients with short bowel syndrome

Jeppesen

2013

Expert Opinion on Orphan Drugs

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Section: Oral Dietmentioning

confidence: 87%

The non-surgical treatment of adult patients with short bowel syndrome

Jeppesen

2013

Expert Opinion on Orphan Drugs

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“…High complex carbohydrate diets in SBS patients with intact colon in continuity with the small intestine are to be emphasized as starch and soluble fiber such as pectin are almost completely metabolized and absorbed in these patients [43]. Other soluble fibers such as oat, oat bran, and barley are also largely undigested in the small bowel and pass through to the colon and are fermented by gut bacteria to SCFA and hydrogen.…”

Section: Carbohydrate (Fiber and Starch) Supplementationmentioning

confidence: 99%

Management and Complications of Short Bowel Syndrome: an Updated Review

Carroll

Benedetti

Schowalter

et al. 2016

Curr Gastroenterol Rep

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Short bowel syndrome (SBS) is defined as loss of bowel mass from surgical resection, congenital defects, or disease. Intestinal failure (IF) includes the subset of SBS unable to meet nutrition needs with enteral supplements and requires parenteral nutrition (PN). The parenteral treatment of SBS is now a half-century old. Recent pharmacologic treatment (GLP-2 analogues) has begun to make a significant impact in the care and ultimate management of these patients such that the possibility of reducing PN requirements in formerly PN-dependent patients is a now a real possibility. Finally, newer understanding and possible treatment for some of the complications related to IF have more recently evolved and will be an emphasis of this report. This review will focus on developments over the last 10 years with the goal of updating the reader to new advances in our understanding of the care and feeding of the SBS patient.

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“…Digestible polysaccharides, such as starch and the soluble fiber pectin, can be an important component of the diet in patients with a jejunocolic anastomosis (Atia et al 2011). In such cases, starch and pectin have been shown to be well tolerated, to contribute a sizable source of energy, and to drive the production of SCFAs.…”

Section: Chos and Scfasmentioning

confidence: 99%

Short bowel syndrome in infants: the critical role of luminal nutrients in a management program

Roy

Groleau

Bouthillier

et al. 2014

Appl. Physiol. Nutr. Metab.

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Short bowel syndrome develops when the remnant mass of functioning enterocytes following massive resections cannot support growth or maintain fluid-electrolyte balance and requires parenteral nutrition. Resection itself stimulates the intestine's inherent ability to adapt morphologically and functionally. The capacity to change is very much related to the high turnover rate of enterocytes and is mediated by several signals; these signals are mediated in large part by enteral nutrition. Early initiation of enteral feeding, close clinical monitoring, and ongoing assessment of intestinal adaptation are key to the prevention of irreversible intestinal failure. The length of the functional small bowel remnant is the most important variable affecting outcome. The major objective of intestinal rehabilitation programs is to achieve early oral nutritional autonomy while maintaining normal growth and nutrition status and minimizing total parenteral nutrition related comorbidities such as chronic progressive liver disease. Remarkable progress has been made in terms of survivability and quality of life, especially in the context of coordinated multidisciplinary programs, but much work remains to be done.

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Macronutrient Absorption Characteristics in Humans With Short Bowel Syndrome and Jejunocolonic Anastomosis: Starch Is the Most Important Carbohydrate Substrate, Although Pectin Supplementation May Modestly Enhance Short Chain Fatty Acid Production and Fluid Absorption

Abstract: Despite malabsorption, starch is the primary carbohydrate substrate for colonic bacterial fermentation in patients with short bowel syndrome, although soluble fiber intake also enhances colonic SCFA production.

Cited by 53 publications

References 63 publications

The non-surgical treatment of adult patients with short bowel syndrome

The non-surgical treatment of adult patients with short bowel syndrome

Management and Complications of Short Bowel Syndrome: an Updated Review

Short bowel syndrome in infants: the critical role of luminal nutrients in a management program

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