Macrodystrophia lipomatosa of the foot: A case report

Abstract

Abstract. Macrodystrophia lipomatosa is a sporadic, nonhereditary developmental anomaly and a rare form of congenital localized gigantism. It is characterized by the proliferation of all the mesenchymal elements of a digit or digits, and a disproportionate increase of fibroadipose tissue involving the nerve sheath, muscle, periosteum and bone marrow. In the present study, a 9-month-old boy was referred to Gazi University Hospital (Ankara, Turkey) with congenital unilateral enlargement of the right forefoot, particularly involving the second and third toes. X-ray and magnetic resonance imaging (MRI) scans were performed in order to assess the skeletal structures. The present study described the characteristic imaging features, with an emphasis on the MRI findings, of this rare congenital form of gigantism.

Macrodystrophia lipomatosa: Clinico-patho-radiological correlation

“…There are osseous hypertrophy and cortical thickening in the affected part of the body, and this may lead to exostoses such as bony outgrowths from the involved bone. [ 8 9 10 ]…”

“…The various differential diagnoses are discussed in Table 1. [1,2,[7][8][9][10] The problems associated with a patient of ML can be cosmetic or mechanical. The overgrowth may lead to interference in normal day-to-day activities or make patient prone to repeated injury.…”

“…There are osseous hypertrophy and cortical thickening in the affected part of the body, and this may lead to exostoses such as bony outgrowths from the involved bone. [8][9][10] The treatment is usually surgical, which is carried out due to cosmetic reasons, but since the digital enlargement stops at puberty, management should include an attempt to preserve neurological functions. For lesion involving median and plantar region, conservative approach has been advocated.…”