MA10.06 Centrality Definition in Non-Small Cell Lung Cancer. Predictor For Occult Mediastinal Lymph Node Involvment

Abstract

89.8% vs. 73.3%, p¼0.004, T1c; 90.0% vs. 62.6%, p¼0.046). Furthermore, clinical T categories significantly separated the OS in Solid arm (p¼0.015) (T1a vs. T1b; p¼0.090, T1b vs. T1c; p¼0.037). In contrast, the 5y-OS was approximately 90% or more in GGO arm despite their T categories. Moreover, regarding radiological and pathological correlations, the rates of AIS was only 65% in Tis, and 51% showed invasive adenocarcinoma even in T1mi. Conclusion: Clinical T category should be considered based on the presence of GGO on thin-section CT, and tumor size should be applied exclusively to radiological solid lung cancer. In contrast, oncological outcomes of the tumor with GGO component were excellent despite their T categories, which should be described as Tis for pure-GGO, and T1a for part-solid tumor.

Is invasive mediastinal staging necessary in intermediate risk patients with negative PET/CT?

“…cN1 was defined by CT when hilar lymph nodes >10 mm in short axis or by FDG-PET/CT when lymph node uptake was higher than the surrounding mediastinal tissue. Centrality was defined as tumor growing in the inner third of the chest in a dedicated CT scan (8). Tumor size was also recorded.…”