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Abstract

We did researches of gas exchange in case of different clinical variants of diabetic ketoacidosis. Distribution of patients were based on clinical variants clinical and laboratory characteristics of the course. Gas exchaange violations are present in all cases of diabetic ketoacidosis and have certain characteristics. The level of carbon dioxide tension and respiratory rate was the lowest under the condition of abdominal and cardiac variants, which were expressed by shortness of breath. In case of nephrotic variant, the tension of carbon dioxide is relatively high, which indicates the participation of the second compensatory mechanisms of metabolic acidosis, in addition to the development of dyspnea. In case of encefalopatia variant of development of DKA fraction of gaseous carbon dioxide dominated, namely only in the form of dissolved carbon dioxide uhich is able to penetrate the blood-brain barrier and to change intracellular pH.