Lysobacter terrestris sp. nov., isolated from soil

Woo, Chae Yung; Kim, Jaisoo

doi:10.1099/ijsem.0.005204

Cited by 5 publications

(1 citation statement)

References 33 publications

(40 reference statements)

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“…What is the relationship between serum metabolites and rumen microbiota? The conjoint analysis revealed that there was a significant positive correlation between the differential metabolite 6-hydroxynicotinic acid and some microbiota from plant soil [53,54] (Lysobacter, Pedomicrobium, and Solirubrobacter) between low and middle altitudes. 6hydroxynicotinic acid is involved in regulating respiratory-related diseases and plays a positive role [55], with the highest content at the mid-altitude of 3500 m, which may be greatly related to this soil microbe at high altitude.…”

Section: Discussionmentioning

confidence: 99%

Synergistic Responses of Tibetan Sheep Rumen Microbiota, Metabolites, and the Host to the Plateau Environment

Sha,

Guo,

et al. 2023

IJMS

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Plateau adaptation in animals involves genetic mechanisms as well as coevolutionary mechanisms of the microbiota and metabolome of the animal. Therefore, the characteristics of the rumen microbiome and metabolome, transcriptome, and serum metabolome of Tibetan sheep at different altitudes (4500 m, 3500 m, and 2500 m) were analyzed. The results showed that the rumen differential metabolites at 3500 m and 4500 m were mainly enriched in amino acid metabolism, lipid metabolism, and carbohydrate metabolism, and there was a significant correlation with microbiota. The differentially expressed genes and metabolites at middle and high altitudes were coenriched in asthma, arachidonic acid metabolism, and butanoate and propanoate metabolism. In addition, the serum differential metabolites at 3500 m and 4500 m were mainly enriched in amino acid metabolism, lipid metabolism, and metabolism of xenobiotics by cytochrome P450, and they were also related to microbiota. Further analysis revealed that rumen metabolites accounted for 7.65% of serum metabolites. These common metabolites were mainly enriched in metabolic pathways and were significantly correlated with host genes (p < 0.05). This study found that microbiota, metabolites, and epithelial genes were coenriched in pathways related to lipid metabolism, energy metabolism, and immune metabolism, which may be involved in the regulation of Tibetan sheep adaptation to plateau environmental changes.

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Section: Discussionmentioning

confidence: 99%