Lyophilized Human Dura as a Bladder Wall Substitute: Experimental and Clinical Results

Kelâmı, A.

doi:10.1016/s0022-5347(17)61563-5

Cited by 78 publications

(20 citation statements)

References 3 publications

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“…Only few clinical studies have been reported. Arikan et al (14) reported the use of Dura matter in 10 patients with NVD to augment the bladder, which had been previously used experimentally by Kelâmi (59). They reported a 2.3-fold increase in BC but the follow up period was not mentioned.…”

Section: Resultsmentioning

confidence: 99%

Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

González¹,

Ludwikowski²

2013

Front. Pediatr.

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Alternatives to conventional enterocystoplasty have been developed in order to avoid the most common complications derived from contact of the urine with intestinal mucosa. In this article critically we review the literature on the topics: ureterocystoplasty, detrusorectomy, detrusorotomy, seromuscular gastroenterocystoplasty, use of off the shelf biomaterials, and bladder augmentation by bioengineering. Recognizing the difficulty of deciding when a child with a history of posterior urethral valves requires and augmentation and that the development of a large megaureter in cases of neurogenic dysfunction represents a failure of initial treatment, we conclude that ureterocystoplasty can be useful in selected cases when a large dilated ureter is available. Seromuscular colocystoplasty lined with urothelium (SCLU) has been urodynamically effective in several series when the outlet resistance is high and no additional intravesical procedures are necessary. Seromuscular gastrocystoplasty lined with urothelium seems to offer no distinct advantages and involves a much more involved operation. The use of seromuscular segments without urothelial preservation, with or without the use of an intravesical balloon has been reported as successful in two centers but strict urodynamic evidence of its effectiveness is lacking. The published evidence argues strongly against the use of detrusorectomy or detrusorotomy alone because of the lack of significant urodynamic benefits. Two recent reports discourage the use of small intestinal submucosa patches because of a high failure rate. Finally, research into the development of a bioengineered bladder constructed with cell harvested from the same patient continues but is fraught with technical and conceptual problems. In conclusion of the methods reviewed, only ureterocystoplasty and SCLU have been proven urodynamically effective and reproducible.

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Section: Resultsmentioning

confidence: 99%

Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

González¹,

Ludwikowski²

2013

Front. Pediatr.

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“…Natural matrices derived from small intestine submucosa (SIS) [17], decellularized bladder matrix (BAM) [18,19], omentum [20–22], pericardium [23,24], peritoneum [25], lyophilized dura [26], and amniotic membranes [27,28] have all been previously reported. In particular, decellularized collagen-based scaffolds including SIS and BAM have demonstrated marginal success in terms of restoring bladder functionality and capacity [17,29–31].…”

Section: Conventional Biomaterials For Bladder and Urethral Defect Rementioning

confidence: 99%

Silk Fibroin Scaffolds for Urologic Tissue Engineering

2016

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Urologic tissue engineering efforts have been largely focused on bladder and urethral defect repair. The current surgical gold standard for treatment of poorly compliant pathological bladders and severe urethral stricture disease is enterocystoplasty and onlay urethroplasty with autologous tissue, respectively. The complications associated with autologous tissue use and harvesting have led to efforts to develop tissue-engineered alternatives. Natural and synthetic materials have been used with varying degrees of success, but none has proved consistently reliable for urologic tissue defect repair in humans. Silk fibroin (SF) scaffolds have been tested in bladder and urethral repair because of their favorable biomechanical properties including structural strength, elasticity, biodegradability and biocompatibility. SF scaffolds have been used in multiple animal models, and have demonstrated robust regeneration of smooth muscle and urothelium. The pre-clinical data involving SF scaffolds in urologic defect repair are encouraging and suggest that they hold potential for future clinical use.

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“…All of them had the common goal of eliminating or diminishing the problems associated with the incorporation of gastrointestinal mucosa into the urinary tract. The variety of natural materials used has included peritoneum (39), omentum (40, 41), fascial free grafts (42), lyophilized human dura (43), bovine pericardium (44) fresh placental membranes (45), and preserved bladder grafts (46), as well as synthetic materials such as polyvinyl sponge (47), gelatin sponge (48), and teflon-felt (49). These are now simply historical anecdotes and will not be discussed further but the extensive work generated does highlight the creativity that has gone into establishing a clinical alternative to enterocystoplasty.…”

Section: Urothelial Preserving Augmentation Techniquesmentioning

confidence: 99%

The Evolution of Bladder Augmentation: From Creating a Reservoir to Reconstituting an Organ

Jednak

2014

Front. Pediatr.

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Bladder augmentation was first described in 1899. The goal at the time was to establish the ideal method to create a simple capacious reservoir for the safe storage of urine. That simple idea has over the last 100 years grown into one of the most dynamic areas in Pediatric Urology. Creative minds and hands from individuals in multiple disciplines have led us from creating a reservoir to the threshold of recreating a functional organ. In this review, we look at the historical evolution of bladder augmentation and how it exponentially grew in scope from those initial descriptions of intestinocystoplasty to the work being reported today in the field of tissue engineering.

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Lyophilized Human Dura as a Bladder Wall Substitute: Experimental and Clinical Results

Cited by 78 publications

References 3 publications

Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

Alternatives to Conventional Enterocystoplasty in Children: A Critical Review of Urodynamic Outcomes

Silk Fibroin Scaffolds for Urologic Tissue Engineering

The Evolution of Bladder Augmentation: From Creating a Reservoir to Reconstituting an Organ

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