Lymphotoxin alpha functional germline genetic variant: A future prognostic factor in colorectal cancer?

Abstract

demonstrated that B cells migrated and proliferated at higher rates towards HMGB1overexpressing cell lines. Conclusions: Our findings indicate that HMGB1 was over-expressed in tumor compared with normal tissue. HMGB1 expression per se was not correlated to survival in our log-rank analysis. HMGB1 expression has probable role in B cells recruitment, migration/proliferation. Legal entity responsible for the study: Dora LW Kwong. Funding: Has not received any funding. Disclosure: All authors have declared no conflicts of interest.24P Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways