Lymphoplasmacyte-Rich Meningioma of the Third Ventricle: Case Report

Abstract

Introduction Meningiomas are the most common primary intracranial tumors, accounting for up to 35% of the neoplasms in this category. Approximately 10–20% of these neoplasms are histologically atypical, and the lymphoplasmacyte-rich meningioma (LPM) corresponds to a very rare subtype of meningioma that is characterized histopathologically by massive infiltrates of inflammatory cells. The case described in the present study is the sixth case of an intraventricular LPM found in the literature and the first case considering the location in the third ventricle. Case Description A 21-year-old male without previous comorbidities sought medical attention due to visual impairment (complaining of intermittent visual blur) for 2 months. A magnetic resonance imaging of the brain confirmed the presence of a well-delimited solid mass in the third ventricle of 3.0 × 2.3 cm with a cystic component that extended itself inferiorly and distorted the visual pathway anatomy. Neurosurgeons decided to access the lesion using an interhemispheric transcallosal approach with a transforaminal access, and the lesion was resected completely. The patient has an ambulatorial endocrinological follow-up and is neurologically stable 6 months after the procedure. No new visual deficits were noted. Conclusion Lymphoplasmacyte-rich meningioma is a very rare intracranial tumor, and the involvement of the third ventricle make this case unique

A rare cystic lymphoplasmacyte-rich meningioma: A case report and review of the literature

“…LRPM, a rare WHO grade I subtype, usually occurs in young and middle-aged patients without sex predominance; in our case, it is even extremely rare since it occurred with a cystic lesion that has been only ten reported in the literature (became 11 with our case). [ 6 , 10 , 11 , 15 , 16 , 20 , 25 , 28 ] LPRM can occur in a various locations,[ 28 ] while, in our case, the lesion was located in the right temporal lobe behind the sphenoid wing extending to parietal lobe. Radiologically, these tumors usually show unclear borders with marked edema and also an invasion of adjacent brain tissue.…”

“…[ 13 , 22 , 27 , 28 ] Among 21 patients [included our case, Table 1 ], the age of diagnosis ranged from 9 to 63 years old (39.2 ± 15.6 years old), and the male-to-female ratio was 10:11. [ 3 , 4 , 6 , 9 , 11 , 12 , 15 , 16 , 19 , 20 , 23 - 26 ] The most common locations were convexity (10/21; frontal 2, parietal 2, occipital 2, frontotemporal 1, frontoparietal 2, and temporoparietal 1), cranial base (4/21; anterior 2, middle fossa 2), falx (1/21), and tentorium cerebelli (1/21). Occasionally, the lesions located at ventricle (4/21; lateral ventricle 1, 3 rd ventricle 1, and trigone 2) and cerebellopontine angle (1/21).…”