Lymphoma of bone with initial presentation as a calvarial mass

Dai, Ming; Ho, Ching Liang; Chen, C. Y.; Chen, T. M.; Yu, Cheng; Chao, Tsu Yi

doi:10.1007/s002770000208

Cited by 14 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Involvement of the cranial vault is an unusual manifestation of non-Hodgkin’s lymphoma in patients without HIV infection. Only fourteen patients with non-HIV related primary cranial vault lymphoma have been reported in the literature [2-15]. Our patient was HIV negative and presented young age in comparison to the literature.…”

Section: Discussionmentioning

confidence: 61%

See 1 more Smart Citation

Successful management of primary non Hodgkins lymphoma of the cranial vault

Fadoukhair¹,

Lalya²,

Amzerin³

et al. 2011

Pan Afr Med Jrnl

View full text Add to dashboard Cite

Primary bone lymphoma (PBL) is a relatively uncommon entity. However, involvement of the cranial vault is an unusual manifestation of aggressive non-Hodgkin’s lymphoma. We report the case of a 42-year old immunocompetent woman who presented with an enlarging mass involving the right parietal bone. Magnetic resonance imaging (MRI) of the brain revealed an expansive tumor that affects the right parietal bone. Computed tomographic (CT) scans of the abdomen, chest and pelvis were negative for lymphadenopathy or organomegaly. Biopsy of the mass showed diffuse large B-cell non-Hodgkin’s lymphoma confirmed by immunohistochemical study. The patient had a complete response after 4 cycles of chemotherapy followed by external beam radiotherapy. After a follow-up of more than 9 months the patient is still in good local control without distant metastasis. The aim of our work is to report a case of Primary bone lymphoma of the cranial vault with good response to treatment combining sequential chemotherapy and radiotherapy.

show abstract

Section: Discussionmentioning

confidence: 61%

“…The femur, tibia and pelvis are the most common skeletal sites [1]. To our knowledge, only fourteen immunocompetent patients with primary cranial vault lymphoma have been reported in the literature [2-15]. Because of the rarity of this entity and the lack of evident literature, its optimal management is still unknown.…”

Section: Introductionmentioning

confidence: 99%

Successful management of primary non Hodgkins lymphoma of the cranial vault

Fadoukhair¹,

Lalya²,

Amzerin³

et al. 2011

Pan Afr Med Jrnl

View full text Add to dashboard Cite

show abstract

“…Typical radiographic images show a large soft tissue component of the permeative growth or a moth-eaten pattern and less cortical destruction. However, this mimics the appearance of other diseases such as Langerhan cell histiocytosis, osteomyelitis, leukemia, plasmacytoma, Ewing sarcoma, and metastatic cancer [1,7]. …”

Section: Discussionmentioning

confidence: 93%

“…The most common clinical manifestations of calvarial lymphomas are painless scalp masses [2,3,7-9], headaches [2,9], convulsions [1], or focal neurologic signs [1]. But these symptoms and signs are nonspecific, so further radiological and histological studies are needed for a conclusive diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Primary Malignant Lymphoma of the Cranial Vault with Extra- and Intracranial Extension

Hwang

Park

et al. 2013

Brain Tumor Res Treat

View full text Add to dashboard Cite

Bone involvement is a common finding in many types of lymphomas, particularly in advanced stages. However, cranial vault affliction has been regarded as an exceedingly rare presentation. Here, we report the case of a patient with cranial vault lymphoma who presented with a scalp mass. An 81-year-old woman presented with a gradually growing and non-painful frontal scalp mass that she noticed one month before admission. It was a flatly elevated, round mass measuring about 6×4×4 cm. Computed tomography and magnetic resonance imaging of the brain revealed a contrast-enhancing intracranial extradural mass at the counter-location of the scalp mass. The superior sagittal sinus was involved at the tumor site. Cerebral angiography showed that the tumor feeding vessels originated from the bilateral external carotid arteries. An operation was performed and the tumors were removed together with the involved bone. The pathologic diagnosis was malignant diffuse large B-cell type lymphoma. The patient was transferred to the Hemato-Oncology department for chemotherapy. Primary lymphoma of the cranial vault with scalp mass is very rare but it should be considered in the differential diagnosis of scalp masses. Although the results of reported cases are variable, the combination of surgery, radiation, and chemotherapy appears to offer favorable outcomes.

show abstract

“…Initial involvement of the calvarium is extremely rare. Table 1 details the 16 previously reported cases in the English literature and our case [3,4,5,6,7,8,9,10,11,12,13,14,15,16]. This is the first case of peripheral B cell lymphoma, Burkitt-like.…”

Section: Discussionmentioning

confidence: 95%

Primary Peripheral B Cell Lymphoma, Burkitt-Like, of the Cranial Vault

Tanimura¹,

Adachi²,

Tanda³

et al. 2005

Acta Haematol

View full text Add to dashboard Cite

We report an autopsy case of malignant lymphoma of the cranial vault. The patient was an 85-year-old woman who exhibited a painless subcutaneous scalp lump associated with no neurological abnormalities. CT scan and magnetic resonance imaging of the head showed an extra-intra cranial isodensity lesion of the cranial vault. Autopsy revealed that the tumor was composed of medium-sized cells which were immunoreactive with CD45, CD20, CD79a, and CD10, and a diagnosis of peripheral B cell lymphoma, Burkitt-like, was made. Non-Hodgkin lymphoma originating from the cranial vault is extremely rare; a search of the English literature revealed only 16 previously reported cases. Herein, we review this singular calvarial lymphoma.

show abstract

Lymphoma of bone with initial presentation as a calvarial mass

Cited by 14 publications

References 0 publications

Successful management of primary non Hodgkins lymphoma of the cranial vault

Successful management of primary non Hodgkins lymphoma of the cranial vault

Primary Malignant Lymphoma of the Cranial Vault with Extra- and Intracranial Extension

Primary Peripheral B Cell Lymphoma, Burkitt-Like, of the Cranial Vault

Contact Info

Product

Resources

About