Lymphoma masquerading as occlusive retinal vasculitis: A case study

Sonne, Scott J.; Shieh, Wen-Shi; Srivastava, Sunil K.; Smith, Bradley T.

doi:10.1016/j.ajoc.2020.100777

Cited by 7 publications

(4 citation statements)

References 30 publications

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“…In any case of suspicion, examinations for staging and imaging of the cranium, should be performed. However, ocular involvement may precede CNS infiltration in 42-92% of cases with PIOL [141]. In PIOL, the IL10/IL6 quotient is increasingly performed in addition to cytology from the vitreous or a retinal biopsy, which is often complicated [142].…”

Section: Masquerade Syndromesmentioning

confidence: 99%

“…Case reports speak of diffuse retinal partly occlusive vasculitis with perivascular exudates and retinal whitening in intraocular lymphoma [143,144]. However, the possibility of idiomatic vasculitis and lymphoma activation due to steroid therapy should also be discussed [141]. Say et al reported a case of vasculitis with diffuse vascular sheathing in a patient with metastatic B-cell lymphoma [145].…”

Section: Masquerade Syndromesmentioning

confidence: 99%

See 1 more Smart Citation

A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments

Agarwal

Rübsam

Bonsen

et al. 2022

JCM

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Retinal vasculitis is characterized by inflammatory involvement of retinal arterioles, venules and/or capillaries and can be associated with a myriad of systemic and ophthalmic diseases. In this review, we have comprehensively discussed the etiologies, clinical manifestations, and presentations of retinal vasculitis. We have also included newer advances in imaging in retinal vasculitis such as OCTA and widefield imaging.

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Section: Masquerade Syndromesmentioning

confidence: 99%

Section: Masquerade Syndromesmentioning

confidence: 99%

A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments

Agarwal

Rübsam

Bonsen

et al. 2022

JCM

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“…Rarely, an intravascular variant of large B cell lymphoma, known as angiotropic lymphoma can cause an ORV like picture [64]. Primary vitreoretinal lymphoma has also been linked to occlusive retinal vasculitis and nonperfusion [65,66]. Amyloidosis can also cause retinal nonperfusion and retinal microangiopathy [67].…”

Section: Masqueradesmentioning

confidence: 99%

Occlusive retinal vasculitis: novel insights into causes, pathogenesis and treatment

Arepalli

Thomas

2022

Current Opinion in Ophthalmology

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Purpose of reviewOcclusive retinal vasculitis (ORV) has a large differential diagnosis and varied therapeutic approaches. This review highlights existing and novel causes and treatment options for ORV. Recent findingsMutations in CAPN5, TREX1, and TNFAIP3 have been associated with dominantly inherited forms of ORV. Various intraocular therapeutics have been shown to occasionally cause ORV; the most recent medications associated with ORV are vancomycin and brolucizumab. In cases of ORV linked to Behc ¸et's disease, clinical trials support the use of tumor necrosis factor alpha inhibitors.

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“…Cases of RV are reported in patients with malignant conditions, including acute leukemia, ocular, or central nervous system (CNS) lymphoma, Hodgkin's lymphoma, metastatic B cell lymphoma, and pineal germinoma. [12][13][14][15][16][17][18][19][20] Given this, malignancy should be considered in the differential diagnosis in patients unresponsive to treatment for RV.…”

Section: Introductionmentioning

confidence: 99%

Treatment of non-infectious retinal vasculitis

2023

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Retinal vasculitis (RV) refers to an entity in which the retinal vasculature is inflamed, frequently with indications of inflammation elsewhere in the eye. Non-infectious RV can be idiopathic or associated with systemic disease, ocular conditions, and malignancy. It can also be classified based on the vessel affected: artery, vein, or both. Due to the lack of strong evidence-based treatment trials and algorithms for RV, physicians must often rely on their experience, which creates great variability in treating this entity. This article provides an overview of various treatment modalities used in the management of non-infectious RV, with a focus on immunomodulatory therapies. We outline a potential stepwise approach of starting with steroids to control the acute inflammation and subsequently changing to immunomodulatory therapy (IMT) for long-term treatment.

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Lymphoma masquerading as occlusive retinal vasculitis: A case study

Cited by 7 publications

References 30 publications

A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments

A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments

Occlusive retinal vasculitis: novel insights into causes, pathogenesis and treatment

Treatment of non-infectious retinal vasculitis

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