Lymphocytic interstitial pneumonia: computed tomography findings in 36 patients

Abstract

Objective: To analyze the computed tomography (CT) findings of lymphocytic interstitial pneumonia (LIP). Materials and Methods: We retrospectively reviewed the clinical and CT findings of 36 patients with LIP, including 25 women and 11 men, with a mean age of 52.5 years (age range, 22-78 years). Results: The main associated diseases with LIP were Sjögren syndrome (42%), human immunodeficiency virus infection (17%), amyloidosis (17%), Sjögren syndrome associated with secondary amyloidosis (11%), idiopathic (8%), and systemic lupus erythematosus (5%). The predominant CT abnormalities were multiple cystic airspaces (n = 35), small nodules (n = 15), ground-glass opacities (n = 13), bronchiectasis and/or bronchiolectasis (n = 8), and thickening of the bronchovascular bundles (n = 8). Other CT findings included reticular opacities (n = 7), calcified nodules (n = 4), airspace consolidation (n = 4), emphysema (n = 3), honeycombing (n = 3), lymph node enlargement (n = 2), mosaic attenuation pattern (n = 1), and cavitated nodules (n = 1). Conclusion: The main CT findings of LIP were multiple cysts, small nodules, and ground-glass opacities.

Noninfectious Granulomatous Lung Disease: Radiological Findings and Differential Diagnosis

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Interstitial lung disease in the course of systemic connective tissue diseases: A common problem for rheumatologists and pulmonologists

“…These lesions can be disseminated, but are located mainly along the bronchovascular bundles, interlobular septa and pleurae. HRCT reveals numerous cysts bilaterally within the pulmonary parenchyma; other possible manifestations include nodules and, less frequently, ground-glass opacities and bronchiectasis [13].…”

Neurofibromatosis type 1

“…A number of recent studies in the radiology literature of Brazil have highlighted the importance of imaging methods in the assessment of the chest( 7 , 8 , 9 , 10 , 11 , 12 ). Among the pulmonary findings on computed tomography scans of the chest, Alves Júnior et al (6) found, in descending order, cysts (in 92.9% of patients), emphysema (in 57.1%), and subpleural bullae (in 42.9%), typically in combination and bilateral.…”