Lymphocytic colitis: a retrospective clinical study of 199 Swedish patients

Clinical significance of colonic intraepithelial lymphocytosis in a pediatric population

“…24,25 However, a specific association of C. difficile infection and colonic intraepithelial lymphocytosis has yet to be well established.…”

Irritable Bowel Syndrome and Microscopic Colitis: A Systematic Review and Meta-analysis

“…The condition is commoner in women, 22 is a frequent cause of an altered bowel habit towards looser stools, 23,24 and is often accompanied by abdominal pain. [25][26][27] The incidence of MC has been reported as 2.6 to 21.0 Kamp et al…”

Diarrhoea is not the only symptom that needs to be treated in patients with microscopic colitis

“…However, these two disease entities can be considered together and stratified for subtypes [1]. Some studies have shown a female predominance in both CC and LC [2], mainly affecting middle-aged women, whereas others have not been able to confirm this in LC [3,4]. The aetiology to MC is unknown, but autoimmunity, inflammation and bile acid malabsorption have been suggested [2,5].…”

“…Several studies have shown a symptomatic overlap between MC and irritable bowel syndrome (IBS) [7,8], and the combination of these two diseases further impairs gastrointestinal symptoms and psychological well-being [8]. The great overlap between IBS and MC, the fact that 63% of MC patients only have a single attack of diarrhoea, and the wide range of conditions rendering secondary MC, may lead to an inaccurate diagnose-setting [1,3,9]. Regarding inflammatory bowel disease (IBD), a consensus has been stated that requires at least one relapse of the disease before a final diagnosis [10].…”