Lymphocyte:Monocyte Ratio At The Start Of Conditioning Regimen Is Associated With Survival Post-Autologous Stem Cell Transplantation (ASCT) For Lymphoma and Myeloma
Abstract:Introduction
Several studies have suggested that an increased peripheral blood absolute lymphocyte count (ALC) at day 15 after ASCT is associated with improved survival and decreased relapse rate. Recently, the ratio of ALC to the absolute monocyte count (AMC) (Lymphocyte:Monocyte Ratio; LMR) has been described as a strong prognostic factor at time of diagnosis in patients with various lymphoid malignancies. In most reports, a LMR cut-off value of less than 1.1 indicates patients who have a w… Show more
“…The relationship between the number of circulating monocytes and clinical outcomes was mainly attributed to their role as precursors of TAM. A prognostic significance was also reported for the LMR (lymphocyte/monocyte ratio) in newly diagnosed myeloma patients [8] and also at the start of the conditioning regimen of autologous stem cell transplantation (ASCT) [9].…”
“…The relationship between the number of circulating monocytes and clinical outcomes was mainly attributed to their role as precursors of TAM. A prognostic significance was also reported for the LMR (lymphocyte/monocyte ratio) in newly diagnosed myeloma patients [8] and also at the start of the conditioning regimen of autologous stem cell transplantation (ASCT) [9].…”
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.