“…American HIV-infected patients, on the contrary, are predominantly homosexual men who probably contracted the infection by anal intercourse. In direct blood-stream infections there is, frequently, an immediate replication of the virus, as documented by the rapid seroconversion observed in such patients Neisson-Vernant et al, 1986;Vittecoq et al, 1986), whereas in sexually-and anally-transmitted HIV-infections, HIV genomes may remain in a latent state for a long period of time (Ranki et al, 1987;Farzedegan et al, 1988;Imagawa et al, 1989). Thus, the differential evolutions of blood-transmitted versus sexually-and anally-transmitted HIV infections might exert peculiar pathogenetic stimuli leading to specific neoplastic diseases.…”