Lycopene and Cardiovascular Diseases

Verghese, M.; Sunkara, Rajitha; Shackelford, L.; Walker, Lloyd T.

doi:10.1201/9780429063602-12

Cited by 3 publications

(5 citation statements)

References 1 publication

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“…Cardiovascular or cardiological diseases are prevalent causes of human health declination and co‐morbidity (Virani et al, 2021). Factors affecting cardiovascular diseases include biological factors, genetic factors, dietary components, oxidative enzymes, antioxidant enzymes, and lifestyles (Verghese et al, 2009). Mostly referred cardiovascular diseases are myocardial infarction or heart attack, heart failure, arterial hypertension, angina, cardiac arrest, stroke, heart failure, coronary artery disease, peripheral artery disease, valvular heart disease, and congenital heart defect (Hasan & Sultana, 2017).…”

Section: Potentials Of Lycopene Against Aging Biomarkers and Aging‐re...mentioning

confidence: 99%

Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

Abir

Mahamud

Tonny

et al. 2023

Food Science & Nutrition

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Aging and aging‐related chronic disorders are one of the principal causes of death worldwide. The prevalence of these disorders is increasing gradually and globally. Considering this unwavering acceleration of the global burden, seeking alternatives to traditional medication to prevent the risk of aging disorders is needed. Among them, lycopene, a carotenoid, is abundant in many fruits and vegetables, including tomatoes, grapefruits, and watermelons, and it has a unique chemical structure to be a potent antioxidant compound. This nutraceutical also possesses several anti‐aging actions, including combating aging biomarkers and ameliorating several chronic disorders. However, no systematic evaluation has yet been carried out that can comprehensively elucidate the effectiveness of lycopene in halting the course of aging and the emergence of chronic diseases linked to aging. This review, therefore, incorporates previous pre‐clinical, clinical, and epidemiological studies on lycopene to understand its potency in treating aging disorders and its role as a mimic of caloric restriction. Lycopene‐rich foods are found to prevent or attenuate aging disorders in various research. Based on the evidence, this review suggests the clinical application of lycopene to improve human health and alleviate the prevalence of aging and aging disorders.

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Section: Potentials Of Lycopene Against Aging Biomarkers and Aging‐re...mentioning

confidence: 99%

Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

Abir

Mahamud

Tonny

et al. 2023

Food Science & Nutrition

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“…From a dietary perspective, researchers have shown that eating tomatoes or other food containing lycopene can reduce the possibility to suffering cardiovascular disease that are chronic [1]. Lycopene has been proved with the properties of lipid lowering, reducing the LDL level, and promoting production of high-density lipoprotein (HDL).…”

Section: Lycopene and Vascular Healthmentioning

confidence: 99%

“…Atherosclerosis accounted for over 50% of CVD. Lipid metabolism disorder is the pathological basis of atherosclerosis, macrophages in lesions promote inflammation and plaque formation and with the cholesterol sediment ceaselessly accumulate in macrophages in the large and medium-sized arteries, its progression may be clinically silenced for a period, then to the point where it directly led to severe consequence such as a heart attack or stroke [1].…”

Section: Cardiovascular Diseasesmentioning

confidence: 99%

“…Hypertension, low HDL and diabetes are also the risk factors for cardiovascular disease. Studies have shown that patients suffering with diabetes have 3 to 5 times possibility to get cardiovascular diseases than ordinary people [1]. Furthermore, several studies have related smoking to rates of cardiovascular disease, the likelihood of suffering CVD among people quitted smoking decreases approaches that of normal people in just 2 years.…”

Section: Risk Factors Of Cardiovascular Diseasesmentioning

confidence: 99%

“…With the aggravation of pressure in modern society, people's sleep and eating habits are becoming more and more irregular. Obesity, tobacco use, physical inactivity, and alcohol consumption-all these detrimental habits lead to an increasing trend in mortality of chronic diseases [1]. Cardiovascular disease (CVD) has been reported to be the main reason of death in the global population, and it continues to increase worldwide.…”

Section: Introductionmentioning

confidence: 99%

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Lycopene: A Natural Antioxidant Carotenoids against Cardiovascular Diseases

Li¹,

Liu²,

Wang³

et al. 2022

HSET

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Cardiovascular disease, as a common disease worldwide, is well known to the public because its risk factors are closely related to people's daily life and its prevalence is increasing year by year. At the same time, with the rise of supplements, lycopene has become an important ingredient in some supplements. Lycopene is contained in a series of edible plants and can also be obtained physically extraction or chemically synthesis. In recent years, the hypolipidemic and antioxidant effects of lycopene were confirmed, and scientists have illustrated some links between lycopene and cardiovascular disease. Although there have been studies on the physical benefits of lycopene in people, few articles have fully addressed the mechanisms by which lycopene prevents cardiovascular disease. Starting from the structure of lycopene and the etiology of cardiovascular diseases, this paper comprehensively analyzed the mechanism of lycopene preventing cardiovascular diseases in different ways. The food sources of lycopene are briefly explained in order to provide a clearer food choice for the population. The reasons for the differences in lycopene bioactivity and absorption were also mentioned. In order to scientifically explain the effect of lycopene supplementation on cardiovascular disease, differences were also shown before and after lycopene supplementation.

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ISOLASI LIKOPEN DARI BUAH TOMAT (Solanum lycopersicum L) dan UJI AKTIVITAS LIKOPEN TERHADAP BAKTERI Salmonella thypi

Dewi

Hakim

Savalas

2019

jppipa, pendidikan ipa, fisika, biologi, kimia

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This research aims to know the effectiveness of lycopene antibacterial, through knowing bending zone lycopene towards salmonella thypi. This research has been success to isolate lycopene through extraction process used reflux method at 60oC temperature, using chloroform and methanol as antisolvent. Lycopene extract got 5,12 mg/100 g, analysis of functional groups by using spectroscopy Fourier Transform InfraRed (FTIR) detected C=C alkena alifatik at 1674,91 dan 1639,65 cm-1 wave length, C-H(CH3) detected at 1378,71 cm-1 wavelength, C-H (stretching) alifatikfunctional groups detected at 2853,12 cm-1 wave length, C-H alkena (stretching) detected at 2924,16 cm-1 wave length, and C-H alkena (bending) detected at 1498,86 cm-1 wave length. Inhibitory zone testing of salmonella thypi used paperdisc method with three repetitions. The mean diameter of the inhibitory zone of bacteria formed in positive control was 33,17 mm, negative control was 0 mm. Mean diameter of bacterial inhibitory zone at 3 % concentration with 3, 68 mm mean diameter and maximal Inhibitory zone at 50 % concentration with 15,12 mm mean diameter . The result of this research shown that lycopene extract has bacterial activity towards salmonella thypi Kewords: Isolation, Lycopene, Salmonella thypi, Antibacterial

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Lycopene and Cardiovascular Diseases

Cited by 3 publications

References 1 publication

Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

Pharmacological potentials of lycopene against aging and aging‐related disorders: A review

Lycopene: A Natural Antioxidant Carotenoids against Cardiovascular Diseases

ISOLASI LIKOPEN DARI BUAH TOMAT (Solanum lycopersicum L) dan UJI AKTIVITAS LIKOPEN TERHADAP BAKTERI Salmonella thypi

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