LXXVII Scleroma in Egypt

Botros, George; Hamilton, Paul; Floyd, Thomas M.; Mufti, Aly; Imam, Ahmed

doi:10.1177/000348945406300415

Cited by 18 publications

(5 citation statements)

References 2 publications

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“…Treatment of rhinoscleroma has been attempted for many decades without much success. Many antibiotics, including streptomycin, 7 aureomycin, 8 rifampicin (both systemic 9 and local 10 ) and ciprofloxacin, 11 have been tried as a treatment, but it is unclear if antibiotics can lead to complete cure.…”

Section: Introductionmentioning

confidence: 99%

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Changes in the pattern of rhinoscleroma in Egypt: updated experience

2019

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ObjectiveThis study aimed to record recent changes in the incidence and clinical and histopathological patterns of rhinoscleroma in the middle of Nile Delta in Egypt.MethodTwenty-eight patients with rhinoscleroma were included in this study. Patients who were attending the Department of Otolaryngology at Tanta University Hospitals from January 2014 to January 2019 were included. Cases were diagnosed by clinical, bacteriological and histopathological data. Nasal biopsies were taken for histopathological and electron microscopy studies. All patients received a twelve-week course of 500 mg ciprofloxacin tablets twice daily.ResultsThe rate of rhinoscleroma was shown to be decreasing compared with previous studies. In this study, the disease mainly affected the nose without involvement of the palate, lips, Eustachian tube or bronchi. Histopathological and electron microscopy analyses showed that most cases were in the atrophic and fibrotic stages rather than the granulomatous stage of disease.ConclusionThe incidence of rhinoscleroma in Egypt is decreasing and its clinical and histopathological patterns are changing to less advanced forms. This may be explained by the improvement in socioeconomic conditions and methods of treatment.

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Section: Introductionmentioning

confidence: 99%

“…This study mentioned that the huge characteristic saddle nose, the involvement of the upper lip, and the perforation of the septum and palate was seldom encountered at that time. 8…”

Section: Introductionmentioning

confidence: 99%

Changes in the pattern of rhinoscleroma in Egypt: updated experience

2019

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“…Scleroma is known to start in the subepithelial tissues and spread by direct continuity to the neighbouring soft tissues. Affection of bone and cartilage is denied (Botros, 1954). However, clinical and radiological examination of some of our cases of rhinoscleroma showed evidence of this affection and in some cases it was extensive (Figs.…”

Section: Fig Iomentioning

confidence: 74%

Some Clinicopathological Observations On Scleroma

Handousa¹,

Elwi²

1958

J. Laryngol. Otol.

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“…Treatment of rhinoscleroma has been researched for decades. Different Systemic antibiotics such as streptomycin, 5 aureomycin, 6 rifampicin, 7 and ciprofloxacin 8 have been tried with variable degrees of success. Topical treatment of rhinoscleroma has also been studied and was associated with reduced costs and side effects.…”

Section: Discussionmentioning

confidence: 99%

Topical ciprofloxacin as treatment for rhinoscleroma in a series of 23 patients

Gamea

Tatawi

El-Naggar

et al. 2021

Clinical Otolaryngology

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Scleroma is a chronic-specific granulomatous disease caused by gram-negative Klebsiella rhinoscleromatis bacilli. It usually affects the upper respiratory tract from the nose to the trachea. The nose tends to be affected in almost all cases, hence the term rhinoscleroma. It is prevalent in rural areas where overcrowding, poor hygiene and deficient nutrition may promote the disease. The disease is en-

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LXXVII Scleroma in Egypt

Cited by 18 publications

References 2 publications

Changes in the pattern of rhinoscleroma in Egypt: updated experience

Changes in the pattern of rhinoscleroma in Egypt: updated experience

Some Clinicopathological Observations On Scleroma

Topical ciprofloxacin as treatment for rhinoscleroma in a series of 23 patients

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