Some Clinicopathological Observations On Scleroma

A Fatal Case of Scleroma

“…It affects the nose, naso-pharynx, larynx and trachea usually in combination but according to Dobrzafiski it may be limited to the trachea (Dobrzafiski, 1951). Handousa and Elwi (1958) state that the granuloma when fully developed may present as either multiple well localized small masses or as a single large tumourlike structure. Pressure atrophy of underlying bone particularly in the nose may occur.…”

Rhinoscleroma—A Clinical Perspective

“…The countries mainly concerned are Poland, Hungary, South-Western Russia, Central America, Indonesia and Egypt. In the latter country Handousa (1958) reports an average of 40 cases seen per annum at one hospital. And it is characteristic of this disease that within these countries, the rhinoscleromatous areas tend to remain well-defined and often quite small.…”

Laryngotracheal resection for post scleromatous laryngeal stenosis

“…Scleroma is a chronic granulomatous disease endemic in Egypt amongst many other countries. An average of 40 cases are seen per year at one hospital as reported by Handousa and Elwi (1958). It has a gradual onset affecting the upper respiratory tract, usually in the nose and extending gradually backwards into the pharynx, larynx and sometimes the trachea and bronchi (Friedmann et al, 1986).…”