LXXV The Treatment of Rhinoscleroma Locally with Aureomycin

el-Mofty, A; Attia, O. M.

doi:10.1177/000348945706600408

Cited by 6 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The effect of Streptomycin and irradiation on Rhinoscleroma (Electron microscopic study) by H. H. TOPPOZADA and H. A. GAAFAR (Alexandria, Egypt) El Mofty and Attia, in 1957, stated that 'the more one deals with cases of scleroma, the more one is convinced that this problem is not yet solved and that more studies and more trials of different types of treatment should be carried out'. The number of tested strains of Klebsiella rhinoscleromatis organisms varies, varying from three (Darrell and Hurdle, 1964) to twenty-three (Mazloum, 1969).…”

mentioning

confidence: 99%

The effect of Streptomycin and irradiation on Rhinoscleroma

Toppozada¹,

Gaafar²

1986

J. Laryngol. Otol.

View full text Add to dashboard Cite

mentioning

confidence: 99%

The effect of Streptomycin and irradiation on Rhinoscleroma

Toppozada¹,

Gaafar²

1986

J. Laryngol. Otol.

View full text Add to dashboard Cite

“…3 Robin K Avery et al reported a patient with extensive nasal rhinoscleroma who achieved pathological and bacteriological resolution with oral ciprofloxacin treatment and the patient previous courses of tetracycline and trimethoprim-sulfamethoxasole. 4 Lydia Badia et al in a case report on a young patient with nasal rhinoscleroma who achieved resolution after treatment withoral ciprofloxacin. 5 In our study, we found that both ciprofloxacin and doxycycline were effective in the early stages of disease.…”

Section: Discussionmentioning

confidence: 99%

“…(1962) and Klassen (1965) performed in vitro sensitivity tests and postulated that chlortetracycline was the best antibiotic in their experience. 4 According to Acuna R.T. (1973) streptomycin alone is less effective when larynx and bronchi are involved and he advised combination of antibiotics therapy in extensive involvement of the lesion. 6 Lawrense A.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Ciprofloxacin vs Doxycycline in Treatment of Rhinoscleroma- A Case-Control Study

Kallapa¹,

Sarkar²,

M³

2017

jebmh

View full text Add to dashboard Cite

BACKGROUNDRhinoscleroma is a chronic inflammatory condition in which deforming masses of tissue distend the nasal cavity. Klebsiella rhinoscleromatis is the causative agent. Antibiotic therapy traditionally consisted of streptomycin and tetracycline. But longterm therapy results in adverse side effects and poor patient compliance, hence this study to search alternative agents. MATERIALS AND METHODSThis is a prospective study of 60 cases of rhinoscleroma visiting to the Department of ENT, KIMS, for a period of two years. RESULTSAfter 8 weeks treatment in the atrophic and granulomatous group, 6 (60%) became histopathologically negative and 4 (40%) remained histopathologically positive. The treatment was continued for another 4 weeks in positive cases and at the end of 12 weeks, 8 (80%) turned histopathologically negative, 2 (20%) remained positive. CONCLUSIONWe conclude that ciprofloxacin is a very good alternative drug compared to doxycycline in the treatment of rhinoscleroma particularly in the early stages of the disease and complete cure can be achieved by early diagnosis and treatment. KEYWORDSRhinoscleroma Therapy, Ciprofloxacin, Doxycycline.HOW TO CITE THIS ARTICLE: Kallapa S, Sarkar SR, Shankar MG. Effectiveness of ciprofloxacin vs. doxycycline in treatment of rhinoscleroma-A case-control study. J. Evid. Based Med.

show abstract

“…More recently, still better results are claimed for the systemic use of terramycin (Folbre et al, 1954) and aureomycin (Zweifach, 1955: Botros et al, 1955-The beneficial effects of local applications of aureomycin and chloramphenicol ointments are also reported by El-Mofty and Attia (1957).…”

Section: Medical Treatmentmentioning

confidence: 99%