The effect of Streptomycin and irradiation on Rhinoscleroma

Toppozada, Hussein H.; Gaafar, H.

doi:10.1017/s0022215100100118

Cited by 9 publications

(2 citation statements)

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“…Enhanced metaplasia of the nasal surface epithelium might increase the surface resistance against repeated invasion with scleroma bacilli present in the nasal cavity. This is in agreement with Toppozada and Gaafar (1986) who stated that this enhanced metaplasia form a mucosal protective barrier against the organism.…”

Section: Discussionsupporting

confidence: 92%

“…The fine granules have been considered to be antibodies against scleroma bacilli (Hoffmann et al, 1973). Toppozada and Gaafar (1986) demonstrated an increased condensation of two types of granules inside the vacuoles of Mikulicz cells after treatment with streptomycin and irradiation; fine granules around the bacilli considered to be antibodies against Klebsiella rhinoscleromatis and coarser granules in the vacuoles indicating a process of intracellular destruction of the organisms and representing a degenerated bacterial matter.…”

Section: Discussionmentioning

confidence: 99%

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The effect of rifampicin on rhinoscieroma: an electron microscopic study

Gamea

El-Tatawi

1990

J. Laryngol. Otol.

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Twenty-five cases suffering from rhinoscleroma were divided into two groups. The first group consisted of 15 patients treated with rifampicin systemically. The other group consisted of 10 patients treated locally with rifampicin in the form of ointment. Electron microscopic study of the pathological changes in the lesions showed that rifampicin is highly effective both systemically and locally in the treatment of rhinoscleroma.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%