Lupus erythematosus associated with erythema multiforme: Does Rowell’s syndrome exist?

Shteyngarts, Ann R.; Warner, Michael; Camisa, Charles

doi:10.1016/s0190-9622(99)70165-9

Cited by 48 publications

(65 citation statements)

References 25 publications

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“…In fact, it has been questioned whether patients with RS are actually affected by the random association between DLE and EM. 6,7,11 Nonetheless, several arguments allow reasonable exclusion of this possibility. First, even if target lesions are virtually indistinguishable from those observed in EM, in RS they do not show the typical preferential localization on the acral sites and mucous membranes.…”

Section: Ccle With Em-like Lesions (Rs): a Distinct Ccle Typementioning

confidence: 99%

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Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis associated with lupus erythematosus

Torchia

Romanelli

Kerdel

2012

Journal of the American Academy of Dermatology

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Section: Ccle With Em-like Lesions (Rs): a Distinct Ccle Typementioning

confidence: 99%

“…[6][7][8][9] These studies lacked a systematic approach to data retrieval and analysis and/or were carried out at a time when the number of published RS cases was still very small.…”

mentioning

confidence: 99%

Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis associated with lupus erythematosus

Torchia

Romanelli

Kerdel

2012

Journal of the American Academy of Dermatology

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“…In most of the cases, the coexistence of LE and EM is seen as a kind of overlap syndrome 4 6. Thus, the genuine character of the disease and existence of the RS as an entity must be critically discussed.…”

Section: Discussionmentioning

confidence: 99%

Rowell syndrome - case report with discussion of significance of diagnostic accuracy

Müller

Hinterberger²,

Vogt³

et al. 2011

Case Reports

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Rowell syndrome is a very controversial condition and though defining diagnosing criteria exist, many previously published cases lack one or more of these criteria. It represents the combination of cutaneous lupus erythematosus and erythema multiforme in one single individual. In order to discuss relevance of diagnostic and defining criteria the authors use a case seen in our outpatient service that was primarily diagnosed as Rowell syndrome. But due to lacking criteria, the authors rediagnosed this patient as an unusual variation of lupus erythematosus.

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“…Cabe anotar que la existencia del síndrome de Rowell ha sido controvertida: inicialmente Rowell reporta cuatro pacientes con lupus eritematoso discoide asociado a eritema multiforme, ANA´s con patrón moteado y anticuerpos anti extracto salino de tejido humano (aún no está claro si estos anticuerpos representaban anti Ro o anti La), perniosis y factor reumatoide positivo (17).…”

Section: Medicinaunclassified

“…También, se han publicado reportes de pacientes, no sólo con lupus discoide sino también lupus agudo o subagudo asociados a lesiones tipo eritema multiforme, que muchas veces tampoco tenían la histología o inmunofluorescencia característica (17,18) .…”

Section: Medicinaunclassified

Necrólisis epidérmica tóxica y lupus eritematoso sistémico

Vélez¹,

Morales²,

Calle³

et al. 2018

CES Med.

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Comparte ResumenEl lupus eritematoso sistémico con manifestación tipo necrólisis epidérmi-ca tóxica es una entidad descrita recientemente y cada vez aparecen más reportes en la literatura. Se describe el caso de una paciente de 15 años con lupus eritematoso sistémico quien presentó una necrólisis epidérmica tóxica extensa, cuyas lesiones iniciales eran tipo eritema multiforme. Se discute el caso a la luz de la literatura actual sobre esta nueva entidad.Palabras clave: Necrolisis epidérmica tóxica; Eritema multiforme; Síndrome de Stevens Johnson; Lupus eritematoso sistémico; Lupus eritematoso cutáneo. AbstractToxic epidermal necrolysis (TEN)-like systemic lupus erythematosus is a recently described entity and more cases are being published in the literature today. We describe the case of a 15-year old patient with systemic lupus erythematosus who developed TEN that initially started with erythema multiforme (EM)-like lesiones. We discuss this case according to the published literature on this new entity.Keywords: Toxic epidermal necrolysis; Erythema multiforme; Stevens-Johnson syndrome; Systemic lupus erythematosus; Cutaneous lupus erythematosus Caso clínicoSe trataba de una niña de 15 años, residente en el departamento de Antioquia, con un cuadro clínico de tres meses de evolución que consistía en edema progresivo de cara y los miembros inferiores, junto a disnea de medianos esfuerzos y artralgias con artritis de ambas manos. Lo anterior asociado a un cuadro de 15 días de evolución de un rash morbiliforme en áreas fotoexpuestas, muy pruriginoso, que posteriormente se generalizó. La paciente consultó a un hospital de segundo nivel de atención, en donde le encontraron, adicionalmente, cifras elevadas de presión arterial.La menor fue hospitalizada por el servicio de medicina Interna y se le inició manejo con esteroides tópicos y antihistamínicos y le fueron solicitados exámenes paraclínicos, que reportaron: Hb 7,2, leucocitos de 5 800 (81 % de neutrófilos y 12 % linfocitos), anti-SM y anti-ADN positivos, anticuerpos antinucleares (ANA´S) reactivos 1:320 con patrón moteado, anti-Ro y anti-La negativos, velocidad de sedimentación globular 60, creatinina 2,05,

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Lupus erythematosus associated with erythema multiforme: Does Rowell’s syndrome exist?

Cited by 48 publications

References 25 publications

Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis associated with lupus erythematosus

Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis associated with lupus erythematosus

Rowell syndrome - case report with discussion of significance of diagnostic accuracy

Necrólisis epidérmica tóxica y lupus eritematoso sistémico

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