Lupus cystitis presenting with hidronephrosis and gastrointestinal
            involvement

A 42-year-old woman presented with chronic fever, abdominal pain, intermittent loose stools and dysuria for 3 months. She had recently developed acute dyspnoea with acute kidney injury. She was found to have a contracted, thick-walled bladder with bilateral hydroureteronephrosis. She underwent bilateral percutaneous nephrostomies, following which her renal function recovered. She satisfied the clinical and immunological features of the Systemic Lupus International Collaborating Clinics criteria for systemic lupus erythematosus (SLE). She was initiated on immunosuppression. Lupus cystitis with a contracted bladder is an uncommon presentation of SLE.

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Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus

John

Varughese

Boaz

et al. 2019

BMJ Case Rep

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Very Severe and Refractory Noninfectious Cystitis in Patients with Systemic Lupus Erythematosus: Potential Role of Rituximab Therapy

Ocampo-Piraquive

Mondragón-Lenis

Rios

et al. 2021

Case Reports in Rheumatology

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Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with various clinical manifestations, including, rarely, a form of interstitial cystitis (lupus cystitis, LC). LC can be asymptomatic and usually has discrete symptoms that improve with conventional therapies available for SLE and/or typical interstitial cystitis. A very severe and refractory form is rarely described. In this study, we present four patients with SLE and a very severe form of noninfectious cystitis refractory to the different forms of treatment described. The clinical descriptions of the cases, demographic factors, manifestations associated with SLE, and clinical and paraclinical manifestations related to cystitis, treatments, and outcomes are provided. A proposal for the pathogenesis of this condition is based on the common findings of these patients, including the fact that three were in SLE remission and all four receiving rituximab as induction and/or maintenance therapy.

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Two complications in patients with systemic lupus erythematosus: lupus cystitis and lupus enteritis

et al. 2022

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Lupus cystitis presenting with hidronephrosis and gastrointestinal involvement

Abstract: Lupus cystitis is a rare and underdiagnosed urinary manifestation of LES and the presence of mild urinary symptoms and abdominal pain may alert about this possibility.

Cited by 3 publications

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Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus

Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus

Very Severe and Refractory Noninfectious Cystitis in Patients with Systemic Lupus Erythematosus: Potential Role of Rituximab Therapy

Two complications in patients with systemic lupus erythematosus: lupus cystitis and lupus enteritis

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