Lupine-Induced Crooked Calf Disease: The Last 20 Years

Alkaloid Profiling as an Approach to DifferentiateLupinus garfieldensis,Lupinus sabinianusandLupinus sericeus

“…Lupines ( Lupinus spp.) are a highly adaptable plant species occurring on western USA rangelands in desert to alpine ecosystems (Kingsbury, ; Lee et al , ). Lupines may contain a variety of piperidine and/or quinolizidine alkaloids which have been proposed to play a role in plant–herbivore interactions and plant–microbe interactions (Wink, ).…”

“…Lupines may contain a variety of piperidine and/or quinolizidine alkaloids which have been proposed to play a role in plant–herbivore interactions and plant–microbe interactions (Wink, ). Additionally, these alkaloids can be acutely toxic and/or teratogenic to livestock, resulting in losses to livestock producers (Kingsbury, ; Lee et al , ).…”

Management Practices to Reduce Lupine-Induced Crooked Calf Syndrome in the Northwest

“…1). 1,2 The anomalies are characterized by the presence of limb twisting or bowing (usually the forelimbs with occasional hind-limb involvement), spinal column deviations affecting the neck and back, and other secondary skeletal defects such as rib cage deformities. Occasional cleft palate in calves is also associated with the syndrome.…”