Lung Ultrasound Findings and Endothelial Perturbation in a COVID-19 Low-Intensity Care Unit

Abstract

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COVID-19 Lung Ultrasound Scores and Lessons from the Pandemic: A Narrative Review

“…When combined with coagulation parameters and compressive ultrasound (CUS), the Soldati protocol proved to be useful in evaluating the length of hospitalization and the need for O2 therapy [39]. Notably, the Soldati score demonstrated being a good predictor of fatality (AUC 0.878, sensitivity 87.5%, specificity 81.7%), and helpful in discerning whether patients would benefit from HFNC or MV [40].…”

“…Several of these scores have been correlated with other laboratory or clinical parameters to increase their utility in clinical settings [39,48]. Notably, Boero et al developed the "COVID-19 Worsening Score" (COWS) [49].…”

“…Several of these scores have been correlated with other laboratory or clinical parameters to increase their utility in clinical settings. [39,48] Notably, Boero et al developed the "COVID-19 Worsening Score" (COWS) [49]. A LUSS >15, in combination with four other variables (P/F ratio, dyspnea at admission, number of comorbidities, and days from symptom onset), is useful in estimating a patient's risk of disease progression and can discriminate those at high or low risk of worsening, with an overall accuracy of 80% and a negative predictive value of 93% [49].…”

Breaking down the clotting conundrum: analyzing the role of plasma tissue plasminogen activator in COVID-19 patients through a systematic review and meta-analysis

“…Only four trials reported t-PA levels in surviving and dead COVID-19 patients [25,33,34]. The t-PA values were respectively: 15.33 ± 8.01 for patients who survived to hospital discharge, and 19.04 ± 11.88 for patients who died in hospital due to COVID-19 (SMD = −0.50; 95% CI: −2.45 to 1.44; p = 0.61; Fig.…”