2009
DOI: 10.1016/j.toxlet.2009.06.647
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Lung injury study by 15 days inhalation exposure of titanium dioxide nanoparticles in rats

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Cited by 7 publications
(2 citation statements)
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“…There have been a limited number of relevant studies done with inhalation and the results have been contradictory. Some studies have reported pulmonary neutrophilia after exposure to TiO 2 nanoparticles whereas others have not [ 15 - 20 ]. Comparison of these ENM is difficult due to different or insufficient methods of particle characterisation.…”
Section: Discussionmentioning
confidence: 99%
“…There have been a limited number of relevant studies done with inhalation and the results have been contradictory. Some studies have reported pulmonary neutrophilia after exposure to TiO 2 nanoparticles whereas others have not [ 15 - 20 ]. Comparison of these ENM is difficult due to different or insufficient methods of particle characterisation.…”
Section: Discussionmentioning
confidence: 99%
“…Alveolar macrophages usually contain enzymatic and non-enzymatic antioxidants that scavenge ROS; however, these are insufficient to prevent oxidative stress and pulmonary damages [35,36]. TNPs have been found to cause pulmonary damage and inflammation [37,38]. Acute exposure to TNP rods and dots for 24 h caused pulmonary and cardiac edema, lung and systemic inflammation, and platelet aggregation [39,40].…”
Section: Respiratory Systemmentioning
confidence: 99%