Lung carcinosarcoma

Vidal, María; Monterde, Vanesa Bernal; Arriaga, Beatriz Amores; Perez, A.; Solares, Sara Serrano; Puyal, María Tobeña

doi:10.1007/s12094-010-0508-6

Cited by 8 publications

(6 citation statements)

References 7 publications

(9 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Final diagnosis is accomplished through histological examination combined with the use of different methods, such as the method of monoclonal antibody reactions. Expression of cytokeratin and vimentin confirm the diagnosis of the tumor [36].…”

Section: Introductionmentioning

confidence: 70%

“…Its clinical characteristics, preoperative diagnostic methods, and prognostic factors are still not completely understood [35]. The diagnosis is often made at a late stage when there is multiple metastasis [36]. Final diagnosis is accomplished through histological examination combined with the use of different methods, such as the method of monoclonal antibody reactions.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Molecular Biology of Lung Carcinosarcoma: A Review of the Literature

Chrysanthakopoulos¹

2021

Trends Int Med

View full text Add to dashboard Cite

Lung Carcinosarcoma (LCS) is a rare, malignant aggressive biphasic tumor with an unfavorable prognosis, high mortality rate, and is composed of a mixture of epithelial and mesenchymal elements. The epithelial or carcinomatous element is most commonly squamous followed by adenocarcinoma, whereas the mesenchymal or sarcomatous element commonly contains the main component of the tumor and shows poorly differentiated spindle cell characteristics. Moreover, other foci of differentiated sarcomatous elements such as chondrosarcoma and osteosarcoma may be observed. LCS accounts for less than 0.1% of all lung cancers, has a poor prognosis due to late diagnosis and early metastases. It has been estimated that the median survival time is 9 (3-25) months, a prognosis poorer than other non-small cell lung carcinomas (NSCLC). According to the most recent 2015 World Health Organization (WHO) classification, pleomorphic carcinoma, giant cell carcinoma, lung blastoma, spindle cell carcinoma, and carcinosarcoma consist a heterogeneous category of primary lung cancer accounting from 0.3% to 3% of all primary lung malignancies, known as lung sarcomatoid carcinoma, depending on the observed morphology. Although genetic mutations of some common lung cancer subtypes have been extensively investigated, the molecular characteristics of LCS and the existence of abnormal target genes still remain unknown.

show abstract

Section: Introductionmentioning

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Molecular Biology of Lung Carcinosarcoma: A Review of the Literature

Chrysanthakopoulos¹

2021

Trends Int Med

View full text Add to dashboard Cite

show abstract

“…The diagnosis is often made at a late stage when there are multiple metastasis. The survival rate at six months is only around 27% [18] . However, intussusception is a rare presentation of metastatic pulmonary carcinosarcoma.…”

Section: Discussionmentioning

confidence: 99%

Sarcomatoid Carcinoma of the lung: A rare case of three small intestinal intussusceptions and literature review

Romano

Grassia

Rossetti

et al. 2015

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

HighlightsThere are rare reports of small intestinal intussusceptions caused by metastatic lung carcinosarcoma.Medical treatment, chemotherapy, and radiotherapy are not active in this kind of tumor, so surgery is the treatment of choice.Surgical treatment plays an important role in lung cancer patients with GI metastasis that cause bowel obstruction, perforation, or massive hemorrhage.This presentation shows the third case in literature.

show abstract

“…Once the tumor is disseminated, most of the patients die within few weeks to months from the progressive disease. [1014]…”

Section: Discussionmentioning

confidence: 99%

Imaging findings of pulmonary carcinosarcoma: A case report

Vohra

Narula

2014

Lung India

View full text Add to dashboard Cite

Pulmonary carcinosarcoma is a rare lung tumor, which contains both malignant carcinomatous and heterotopic sarcomatous components. There are only few case reports on the imaging diagnosis of this rare tumor. Herein, we present the radiological findings of this rare tumor, which was suspected on computed tomography (CT) scan due to atypical CT findings of malignant lung mass (not usually seen in bronchogenic carcinoma) and was finally confirmed histologically.

show abstract

Lung carcinosarcoma

Cited by 8 publications

References 7 publications

Molecular Biology of Lung Carcinosarcoma: A Review of the Literature

Molecular Biology of Lung Carcinosarcoma: A Review of the Literature

Sarcomatoid Carcinoma of the lung: A rare case of three small intestinal intussusceptions and literature review

Imaging findings of pulmonary carcinosarcoma: A case report

Contact Info

Product

Resources

About