Lung cancer in a defined geographical area: history and histological types.

Abstract

Lung cancer was diagnosed in 446 patients during four years in a population living in a defined geographical area in northern Finland. The series comprised 420 men and 26 women, with a male/female ratio of 16-6:1. The diagnosis was confirmed histologically or cytologically in 431 cases (97 %). Epidermoid carcinoma was the most common histological type of tumour in the men, followed by small cell anaplastic and adenocarcinoma, whereas in the women all these types were of equal frequency. Almost all the men, but only about half of the women, were smokers or ex-smokers. The amount smoked daily had no correlation with the histological type of cancer, whereas those patients who had started smoking early had relatively more Kreyberg group I tumours (epidermoid, small cell, and large cell carcinoma) than those who had started smoking late. Cancer was usually detected on the basis of symptoms, but 17% emerged from mass radiography or some health examination, and 12 % from examinations for another disease. Fifteen per cent of the patients had no symptoms at the time of diagnosis, this being more common among the patients with epidermoid or adenocarcinoma than among those with anaplastic forms.

Akciğer kanserinde sağkalımı etkileyen klinikopatolojik özellikler

“…Huhti ve arkadaşları, 20 yıllık bir süreçte akciğer kanserli kadın hasta oranının % 6'dan % 15'e yükseldiğini saptamışlardır [7,18]. Sağlık Bakanlığı verilerine göre, 1999 yılında akciğer kanseri insidansı erkeklerde 7.8/100.000, kadınlarda 1.2/100.000'dir [5].…”

Pain experienced by lung cancer patients: a review of prevalence, causes and pathophysiology

“…Two studies reported pain prevalence by underlying histological subtype: Hopwood et al found that 50% of patients with SCLC and 65% of patients with NSCLC had pain [20], whereas in Huhti et al's study these values were 40 and 26%, respectively [21]. Chute et al did not find any relationship between presence of pain and underlying histological subtype [22].…”

“…Of the three studies that assessed the influence of gender on pain, none found a relationship [21,28,29], although Huhti et al found in one small sample (n = 26) that women with pain were more likely to have had it as a long standing problem (defined as more than 6 months duration) than men (P = 0.05) [21].…”

“…Huhti et al found that 20% of patients had had pain for more than 6 months prior to the diagnosis of lung cancer [21]. Portenoy et al found that the median duration of pain experienced by lung cancer outpatients was 4 weeks, but the range was large: 1-177 weeks [30].…”

How Have We Diagnosed Early-Stage Lung Cancer without Radiographic Screening? A Contemporary Single-Center Experience

“…[7], [8] How these cases currently come to medical attention and are diagnosed is not known, as most studies describing the presentation of lung cancer were performed 25–45 years ago, a time when almost all cases were detected by CXR ordered to evaluate cardiopulmonary symptoms. [9]–[14] We therefore evaluated the presentation of early-stage lung cancer in a contemporary population, with particular focus on the type and reason for initial imaging studies. Of these cases, we determined which would have been eligible for the NLST.…”