Lung abscess due to Streptococcus intermedius associated with SARS CoV‐2 infection in pregnancy: Unusual presentation and complication of a commensal bacteria during pregnancy

Abstract

Streptococcus intermedius is a commensal bacterium reported in a few cases as the causative agent of brain and lung abscesses, pneumonia, and endocarditis. Lung abscesses due to Streptococcus intermedius are rare, especially in pregnancy. We describe the first case of lung abscess due to Streptococcus intermedius in a pregnant woman.

Streptococcus intermedius Brain Abscess with Lung Abscess and Aortic Valve Endocarditis: A Case Report and Literature Review

“…We reviewed the available medical literature by PubMed with the keywords “ Streptococcus intermedius ” AND “lung abscess”, “pleural effusion” and “pleural empyema” from 1993 to 2023, published in English. We found 34 articles meeting the inclusion criteria ( Table 2 ), of which 4 described concomitant brain and lung abscesses, but none reported the presence of lung and brain abscesses due to S. intermedius associated with left sided endocarditis [ 1 , 2 , 8 , 9 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 ]. Only one paper [ 8 ] described the case of a lung and brain abscess associated with Chiari network endocarditis in the right heart.…”

“…Risk factors for S. intermedius pleuropulmonary disease include smoking, alcoholism, dental diseases, chronic obstructive pulmonary disease, malignant neoplasms, liver cirrhosis, and diabetes [ 9 ]. Our patient had dental lesions that could have caused bacteremia and aortic valve endocarditis, with a brain abscess as a hematogenous spread complication.…”

“…Streptococcus intermedius has been frequently associated with brain and liver abscesses, in rare cases related to endocarditis or congenital heart diseases [ 3 , 4 , 5 , 6 , 7 , 8 ]. Pleuropulmonary infections by this agent are uncommon [ 9 ], but are increasingly recognized. Absolutely anecdotal is the association of lung and brain abscesses due to S. intermedius with endocarditis [ 8 ].…”

Streptococcus intermedius Brain Abscess with Lung Abscess and Aortic Valve Endocarditis. A Case Report and Literature Review

“…We reviewed the available medical literature by PubMed with the keywords "Streptococcus intermedius" AND "lung abscess", "pleural effusion" and "pleural empyema" from 1993 to 2023, published in English. We found 34 articles meeting the inclusion criteria (Table 2), of which 4 described concomitant brain and lung abscesses, but none reported the presence of lung and brain abscesses due to S. intermedius associated with left sided endocarditis [1,2,8,9,. Only one paper [8] described the case of a lung and brain abscess associated with Chiari network endocarditis in the right heart.…”