Luminescent Metal–Organic Framework Thin Films: From Preparation to Biomedical Sensing Applications

Abstract

Metal-organic framework (MOF) thin films are receiving increasing attention in a number of different application fields, such as optoelectronics, gas separation, catalysis electronic devices, and biomedicine. In particular, their tunable composition and structure, accessible metal sites and potential for post-synthetic modification for molecular recognition make MOF thin films promising candidates for biosensing applications. Compared with solution-based powdery probes, film-based probes have distinct advantages of good stability and portability, tunable shape and size, real-time detection, non-invasion, extensive suitability in gas/vapor sensing, and recycling. In this review, we summarize the recent advances in luminescent MOF thin films, including the fabrication methods and origins of luminescence. Specifically, luminescent MOF thin films as biosensors for temperature, ions, gases and biomolecules are highlighted.

Structure of a Luminescent MOF-2 Derivative with a Core of Zn(II)-Terephthalate-Isoquinoline and Its Application in Sensing of Xylenes

“…There is a growing interest in the development of photoluminescent metal-organic materials (MOMs) [1][2][3][4], where the color emission upon excitation is a significant feature of these materials that has been recently used in several applications such as emitting devices/materials [5,6], optical sensing of vapor phase analytes [3,7], detection of ions [8,9], bioanalytes [10], explosives [11,12], and detection of volatile organic solvents (VOCs) [8,13,14]. Most known MOMs-based chemosensors for organic solvents act in a "turn-off" response where the fluorescence intensity of the compound is quenched upon addition of the analyte [7,15,16].…”

Metal–Organic Framework Thin Films: Fabrication, Modification, and Patterning

“…Several excellent reviews focusing on MOFs, including MOF-TFs, have been published [37,[69][70][71][72][73][74][75][76][77]. These papers review existing and potential applications, as well as the synthesis methods of MOF-TFs.…”

“…Nowadays, MOFs are available in various structures, such as nanocrystals (NCs) [27], nanospheres [28], nanosheets [29], needles [30], hierarchical monoliths [31], thin films (TFs) [32], membranes [33], and glasses [34][35][36]. Among these structures, MOF-TFs are drawing increasing attention due to their tremendous potential in the development of nanotechnology-enabling applications, such as optics [37], photonics [38], electronics [39], catalytic coatings [40], sensing [41][42][43][44], solar cell [45], battery [46], and supercapacitor [44]. One thing to notice is that MOF-TFs cannot be differentiated from MOF membranes by their chemical composition or by their selection of substrates.…”

Infrared crystallography for framework and linker orientation in metal–organic framework films

“…1 Their elds of applications are equally manifold and include photonics, 2 energyrelated applications such as solar or fuel cells, 3,4 homogeneous and heterogeneous catalysis, 5,6 gas and fuel storage, 7,8 or (bio-)sensing. [9][10][11] While MOFs are available in a great variety of shapes, such as nanocrystals, nanospheres, or hierarchical monoliths, MOF thin lms hold tremendous potential to translate the structural properties of individual crystals to continuous, scalable materials. Scalability and processability are essential for the application of MOFs in numerous elds 12,13 such as optics, 9 photonics, 2 catalytic coatings, sensing, solar cells or for batteries.…”