Luminescence nanomaterials for biosensing applications

Abstract

Due to their capacity to immobilize more bioreceptor parts at reduced volumes, nanomaterials have emerged as potential tools for increasing the sensitivity to specific molecules. Furthermore, carbon nanotubes, gold nanoparticles, polymer nanoparticles, semiconductor quantum dots, nanodiamonds, and graphene are among the nanomaterials that are under investigation. Due to the fast development of this field of research, this review summarizes the classification of biosensors using the main receptors and design of biosensors. Numerous studies have concentrated on the manipulation of persistent luminescence nanoparticles (PLNPs) in biosensing, cell tracking, bioimaging, and cancer therapy due to the effective removal of autofluorescence interference from tissues and the ultra‐long near‐infrared afterglow emission. As luminescence has a unique optical property, it can be detected without constant external illumination, preventing autofluorescence and light dispersion through tissues. These successes have sparked an increasing interest in creating novel PLNP types with the desired superior properties and multiple applications. In this review, we emphasize the most recent developments in biosensing, imaging, and image‐guided therapy whilst summarizing the research on synthesis methods, bioapplications, biomembrane modification, and the biosafety of PLNPs. Finally, the remaining issues and difficulties are examined together with prospective future developments in the biomedical application field.

Smart and intelligent optical materials for sensing applications

“…Kumar et al [21] highlighted persistent luminescence NP (PLNP) synthesis methods. The author discussed that PLNPs has varying applications such as in biosensing, cancer therapy, bioimaging, and cell tracking.…”

Electrochemical Sensing of Uric Acid with Zinc Oxide Nanorods Decorated with Copper Oxide Nanoseeds

“…Currently, there have been increasing reports of nanomaterial-based non-enzymatic sensors for detection of different analytes. − Different nanostructures of nanomaterials (i.e., CuO, cuprous oxide (Cu 2 O), ZnO, manganese dioxide (MnO 2 ), iron­(III) oxide (Fe 2 O 3 ), nickel oxide (NiO), cerium­(IV) oxide (CeO 2 ), tungsten disulfide (WS 2 ), cobalt oxide (Co 3 O 4 ), tin­(IV) oxide (SnO 2 ), molybdenum disulfide (MoS 2 ), MXene, carbon black, etc.) and their nanocomposites (i.e., ZnO-CuO, ZnO-Au, ZnO-Fe 2 O 3 , ZnO-polyaniline, ZnO-MWCNTs, etc.)…”

A ternary nucleotide–lanthanide coordination nanoprobe for ratiometric fluorescence detection of ciprofloxacin

“…At the same time, LnCPs can also inherit the unique optical, catalytic, and magnetic properties of lanthanides. Therefore, LnCPs have shown great application potential in biosensing [33][34][35][36], bioimaging [37], drug delivery [38], catalytic reaction [39,40], adsorption and separation [41], environmental monitoring [42], and so forth. Owing to the unique luminescent properties of lanthanide, LnCPs can serve as an effective luminescent sensing platform.…”