&lt;title&gt;Optical coherence tomography: potentialities in clinical practice&lt;/title&gt;

Zagaynova, Elena V.; Gladkova, Natalia D.; Шахов, А. В.; Terentjeva, Anna; Snopova, Ludmila B.; Kuznetzova, Irina A.; Streltzova, Olga; Shakhova, Natalia M.; Kamensky, Vladislav A.; Gelikonov, Grigory V.; Gelikonov, Valentin M.; Kuranov, Roman V.; Myakov, Alex

doi:10.1117/12.580771

Cited by 4 publications

(2 citation statements)

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“…Later, our group made the first clinical studies of OCT capabilities for diagnosis of different clinical states of urinary bladder [11]. Further, the accumulated clinical material enabled us to carry out preliminary statistical studies [44]. The sensitivity and specificity of OCT in detecting urinary bladder neoplasia were analysed on the basis of different statistical samplings.…”

Section: Discussionmentioning

confidence: 99%

“…We made two clinical OCT studies of urinary bladders: in the Nizhny Novgorod regional hospital (Russia) [11,44,45] and in The George Washington University (GWU) Medical Center (USA) [12,45]. We combined available flat-lesions data from both the Russian and the GWU studies to include 80 patients with 114 sites of OCT images with histopathology and cystoscopy data.…”

Section: Urinary Bladdermentioning

confidence: 99%

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Endoscopic OCT with forward‐looking probe: clinical studies in urology and gastroenterology

Zagaynova

Gladkova

Shakhova

et al. 2008

Journal of Biophotonics

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In the current paper we present results of application of endoscopic time-domain OCT (EOCT) with lateral scanning by forward looking miniprobe. We analysed material of clinical studies of 554 patients: 164 patients with urinary bladder pathology, and 390 with gastrointestinal tract pathology. We reviewed the materials obtained in different clinics using the OCT device elaborated at the Institute of Applied Physics. We demonstrate results of EOCT application in detection of early cancer and surgery guidance, examples of combined use of OCT and fluorescence imaging. As a result, we show the diagnostic accuracy of EOCT in specific clinical tasks. The sensitivity of EOCT cancer determination in Barrett's esophagus is from 71% to 85% at different stages of neoplasia with specificity 68% for all stages. As for bladder carcinoma, the sensitivity and specificity are 85% and 68%, respectively. In colon dysplasia EOST demonstrates high efficacy: sensitivity 92% and specificity 84%.

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Section: Discussionmentioning

confidence: 99%