<title>Mueller matrices mapping of biological tissue architectonics</title>

Prognostic heterogeneity of diastolic abnormalities along left ventricular remodeling continuum according to survival rates and laser polarimetry of blood

“…16,9 (16,5-19,6) р 1 < 0,001 р 2 = 0,012 8,1 (5,(9)(10)(11)7) e sept , sm/s 9,4 (7,9-11,5) 6,9 (5,8-7,6) 3,9 (3,8-4,2) р 1 < 0,001 -* e lat , sm/s 13,7 (11,(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)9) 8,5 (6,6-10,2) 4,6 (4,3-5,7) р 1 = 0,005 -* e av , sm/s 11,5 (10,8-12,1) 7,5 (6,9) 4,5 (4,2-4,8) р 1 < 0,001 -* р 1 -statistical significance of difference P 1 vs. P 3 ; р 2 -statistical significance of difference P 2 vs. P 3 ; р 3 -statistical significance of difference P 1 vs. P 4 ; р 4 -statistical significance of difference P 2 vs. P 4 ; * -analyzed in case of sinus rhythm Thus, the continuum of remodeling patterns of LV is characterized by the increase of frequency of constellation of AH/CAD in P 2 if compared with P 1 (χ 2 = 4.232, df = 1, p = 0.040; the accurate Fisher's test p = 0,070) with its 100% frequency with P 3 and P 4 ; progressing of systolic and DD of LV; clinical manifestation of HF; the growth of anisotropy of the erythrocytic suspension in the form of the increase of the values of statistical moments of the 2 nd -4 th order of its laser images' polarization maps. The average age of P 1 patients is statistically significantly lower than that of the other three patterns.…”

“…) registering polarizationally heterogeneous field of erythrocytic suspension smears [6][7][8]14 . The material was statistically analyzed using the software suites Statistica v. 8.0 (StatSoft Inc., USA) and Minitab v. 16.0 (SafeNet Inc., USA).…”

“…These properties determine the ability of an erythrocyte to transform the parameters of laser radiation by the emergence of elliptically polarized laser waves and the possibility to analyze polarization heterogeneity of the images of smears of erythrocytic suspension by way of laser polarimetry 8,14 . Taking into account all mentioned above, it can be assumed that the changes of polarimetric properties of erythrocytes on the stages of cardiovascular continuum represent potential additional, sufficient prognostic "modifier" of HF syndrome and studying them is important concerning the integrative approach to understanding the process of myocardium remodeling.…”

“…it demands being further improved and supplemented with other sufficient prognostic parameters. The disorder of functional properties of erythrocytes as the corpuscles of integrative environment -blood -can be regarded as a potential "modifier" of HF syndrome [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] . Modern literature does not contain enough data as to the erythrocytes functional properties positioning in the integral aspect as possible predictors of myocardium state and the prognosis as to its remodeling.…”

Laser spectrophotometry as biophysical method for endothelin-1 determing content in patients with arterial hypertension

“…Вступ. На даний час налічується кілька тисяч методів аналізу рідких біологічних середовищ, у ході яких визначається концентрація більше ста речовин [1]. Серед інших важливе місце посідають методи аналізу рідких біологічних середовищ, які базуються на кількісному ультрафіолетовому абсорбційному спектральному аналізі (УФ спектрофотометрії) [2].…”