Science is one of the most robust conceptual constructs developed by human beings. Theoretical physical models have been developed involving the smallest and the largest systems over the full scale of the universe. At either extreme, the models, which provide for constant interaction forces between their components, describe experimental observations and are predictive.Life evolved from systems of intermediate size in relation to the extremes of universal scale. Life, biological organs, and cells develop functions only under chemical driving conditions. Natural organs can be considered as biological devices that are very efficient in transforming chemical energy at constant temperature into functions, unlike servitude of machines to the Carnot cycle. Inside any living cell, thousands of simultaneous reactions occur. Every reaction promotes changes from reactants to products, with subsequent changes to hundreds of intramolecular and intermolecular interactions. Moreover, most of those reactions link conformational changes of biopolymers with ionic and electronic movement driving water flow. Hence, many simultaneous chemical reactions, intermolecular, and intramolecular interactions involving conformational movements are outside the possibilities of current theoretical models. Theoretical descriptions of any living cell and predictions of its behavior when unhealthy are unavailable within our scientific models. This constitutes the proximity paradox [1] because we have been able to develop good and predictive theoretical models for subatomic or galactic systems, far removed from our everyday surroundings.Actuation of natural organs such as muscles involves, moreover, the chemical reaction of ATP hydrolysis simultaneous with sensing processes that provide living creatures with a perfect consciousness of both the characteristics of their mechanical movements and their interactions with their environment: they are intelligent machines.Most of our technological developments were inspired by biological functions and organs. One of our aims is to overcome the efficiency of the biological Electropolymerization: Concepts, Materials and Applications. Edited by Serge Cosnier and Arkady Karyakin