&lt;title&gt;Laser shaping of cartilage&lt;/title&gt;

Sobol, Emil N.; Баграташвили, В. Н.; Omelchenko, Alexander I.; Sviridov, Аlexander P.; Helidonis, Emmanuel S.; Kavvalos, George; Christodoulou, Panayiotis; Naoumidi, Irini; Velegrakis, George A.; Ovchinnikov, Yuriy M.; Shechter, A.

doi:10.1117/12.184919

Cited by 30 publications

(38 citation statements)

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“…The fraction of degraded collagen in nasal septal cartilage after reshaping does not exceed that in non-irradiated samples. These observations are consistent with the absence of direct histological observation of laser-induced alterations in cartilage structure in the first studies of laser reshaping of cartilage [6,22]. Nevertheless, future examination of cartilage matrix structure revealed some ultra structure alterations resulting from laser irradiation.…”

Section: Phase Transformations and Chemical Processes During Laser Irsupporting

confidence: 89%

Laser reshaping and regeneration of cartilage

et al. 2007

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Demonstration of laser-induced stress relaxation in cartilage in 1992 led to the development of a novel laser surgical procedure in otolaryngology for the non-ablative reshaping of cartilage. Follow-up studies found that non-destructive laser irradiation may activate regeneration processes in cartilaginous tissue. Ongoing studies seek to characterize the physical, chemical and biological processes and mechanisms involved in the reshaping and regeneration of deformed and diseased cartilage under moderate laser heating. A theoretical model is developed considering laser-induced stress relaxation in cartilage as a process of micropore formation. Results obtained provide scientific and engineering data for development of novel laser surgical procedures for correction of the nasal septum and treatment of spine disc cartilage diseases. This review is aimed to present state of art and recent results in laser -induced reshaping and regeneration of cartilage.Histological cross-section of porcine nasal septal cartilage after laser reshaping using 1.56 µm laser radiation with power of 1.5 W, spot diameter 2 mm, exposure time of 5 s. Stained with Hematoxylin and Eosin, ×400

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Section: Phase Transformations and Chemical Processes During Laser Irsupporting

confidence: 89%

Laser reshaping and regeneration of cartilage

et al. 2007

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“…Several publications have shown that the new shape of cartilage became stable if was heated up to about 708C [3]. A recent study performed by Diaz et al clearly indicated that within this temperature range, chondrocyte viability was compromised [22].…”

Section: Discussionmentioning

confidence: 99%

“…In 1993, Sobol et al demonstrated cartilage reshaping using a laser was possible and pioneered the use of lasers for the correction of cartilaginous deformities in the head and neck [1][2][3]. Several wavelengths have since been evaluated: Diode laser (l ¼ 0.98 mm) [4], Nd:YAG laser (l ¼ 1.32 mm and l ¼ 1.44 mm) [5][6][7], Ho:YAG laser (l ¼ 2.1 mm) [8], Er:YAG laser (l ¼ 2.94 mm) [9] and CO 2 laser (l ¼ 10.6 mm) [10].…”

Section: Introductionmentioning

confidence: 99%

Laser cartilage reshaping in an in vivo rabbit model using a 1.54 μm Er:Glass laser

Mordon

Wang²,

Fleurisse

et al. 2004

Lasers Surg Med

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“…Thermochondroplasty is a promising new technique in which living cartilage is altered by laser beam application and remains viable afterward. Sobol et al 4 suggest that cartilage stress relaxation is due to a phase transformation of water molecules from a bound state (binding to proteoglycans or collagen) to a free or mobile state.…”

mentioning

confidence: 99%

“…Cartilage can be reshaped when heated to approximately 60°C to 75°C. 3 Sobol et al 4 pioneered the development of this procedure and suggested that stress relaxation is owing to a phase transformation of water molecules from a bound state (binding to proteoglycans or collagen) to a free or mobile state. Microscopic findings showed distortion of the proteoglycans and alterations in the collagen skeleton.…”

mentioning

confidence: 99%

In Vitro Enzymatic Treatment and Carbon Dioxide Laser Beam Irradiation of Morphologic Cartilage Specimens

Hajiioannou

Nikolidakis²,

Naumidi³

et al. 2006

Arch Otolaryngol Head Neck Surg

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Objectives: To determine the role of the main cartilage components in the internal system of interlocked stresses and to clarify the effect of laser beam irradiation on cartilage.Design: Control and experimental series.Subjects: Rabbit ear cartilage.Intervention: Rabbit ear cartilage strips incubated in collagenase and hyaluronidase enzyme solutions for specific periods were examined, and the observed changes in shape, strength, and elasticity were recorded, as well as the effect of carbon dioxide laser irradiation. Laserpretreated cartilage strips were also incubated in the enzyme solutions to determine whether the laserprovoked changes were susceptible to enzymatic action. All cartilage pieces were examined by light and electron microscopy.Results: Collagenase-treated cartilage strips gradually lost their interlocked stresses, while hyaluronidasetreated strips mostly maintained their shape and their physical characteristics. Hyaluronidase-incubated cartilage strips altered their shape when they were laser treated. Collagenase-treated cartilages did not modify their shape when they were laser treated. Laser-pretreated cartilage pieces lost their new form in collagenase solutions but kept their laser-evoked shape when put in hyaluronidase solutions. Conclusion:The macroscopic observations combined with light and electron microscopy findings argue for the distinct role of the collagen network in morphologic cartilage shape and tensile strength preservation and provide a probable mechanism of cartilage transformation owing to carbon dioxide laser irradiation.

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<title>Laser shaping of cartilage</title>

Cited by 30 publications

References 0 publications

Laser reshaping and regeneration of cartilage

Laser reshaping and regeneration of cartilage

Laser cartilage reshaping in an in vivo rabbit model using a 1.54 μm Er:Glass laser

In Vitro Enzymatic Treatment and Carbon Dioxide Laser Beam Irradiation of Morphologic Cartilage Specimens

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