Abstract:Aim: To evaluate the impact of rh-GH replacement therapy on neurotransmitters: gamma -amino butyric acid (GABA), dopamine (DA) and serotonin (5-HT) in growth hormone deficient children Research design and methods: This retrospective study included 30 subjects with growth hormone deficit clinically established: 20 boys (5-14 years) and 10 girls (6-14 years). All of them underwent GH replacement therapy from 9 months -10.6 years. rh -GH dose varied in all subjects from 0.6-1.9 mg/day based on detailed clinical a… Show more
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