&lt;p&gt;The Positive Predictive Value of Hip Fracture Diagnoses and Surgical Procedure Codes in the Danish Multidisciplinary Hip Fracture Registry and the Danish National Patient Registry&lt;/p&gt;

Hjelholt, Thomas Johannesson; Edwards, Nina M; Vesterager, Jeppe Damgren; Kristensen, Pia Kjær; Pedersen, Alma B

doi:10.2147/clep.s238722

Cited by 37 publications

(28 citation statements)

References 23 publications

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“…Our sample size (n = 15,717) was much greater than those reported in similar validation studies. 14 , 17 The large population-based sample and the small differences in characteristics of women who were excluded from the current analyses support the generalizability of the results. In addition, we believe that our data are more reflective of the general Japanese population than past findings in other regional cohorts to date because geographical variation is minimized by the nationwide scope of the JNHS.…”

Section: Discussionsupporting

confidence: 56%

Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Kurabayashi¹,

Ideno²,

Nagai³

et al. 2021

CLEP

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Purpose: Although the validity of self-reported osteoporosis is often questioned, validation studies are lacking. This study was performed to investigate how well self-reported diagnoses of osteoporosis agreed with validated clinical information in young and middle-aged women in the Japan Nurses' Health Study (JNHS), a nationwide prospective cohort study of nursing professionals. Patients and Methods: Data were reviewed for 15,717 subjects from the combined cohorts of the JNHS and a preceding pilot study (Gunma Nurses' Health Study). The subjects' mean age at the baseline (BL) survey was 41.6 ± 8.3 years, and the mean followup period was 11.5 ± 4.4 years. Participating nurses were mailed a follow-up questionnaire every 2 years. Respondents who self-reported a positive osteoporosis diagnosis during the study period were sent an additional confirmation questionnaire to corroborate the details. Results: The number (proportion) of women with osteoporosis was 884 (5.6%) [primary osteoporosis, 812 (5.2%); secondary osteoporosis, 72 (0.5%)]. The cumulative incidence of osteoporosis at the age of 40, 50, 60, 70, and 80 years was estimated to be 0.1% (95% confidence interval, 0.1-0.2), 1.1% (0.9-1.3), 7.7% (7.0-8.4), 23.6% (21.6-25.7), and 54.2% (40.2-68.1), respectively. For BL and regular follow-up + expert review versus BL and regular follow-up + confirmation questionnaire + expert review, the positive predictive value (PPV) was 61.3% versus 85.6% and the negative predictive value (NPV) was 98.9% versus 98.2%, respectively. Conclusion: Self-reporting was associated with a high NPV for the incidence of osteoporosis. Although the PPV was slightly lower, additional corroborations by confirmation questionnaire might improve the PPV.

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Section: Discussionsupporting

confidence: 56%

Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Kurabayashi¹,

Ideno²,

Nagai³

et al. 2021

CLEP

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“… 12 The positive predictive value of the hip fracture diagnosis is between 90% and 98% depending on fracture type. 13 …”

Section: Methodsmentioning

confidence: 99%

“…12 The positive predictive value of the hip fracture diagnosis is between 90% and 98% depending on fracture type. 13 The Danish National Health Service Prescription Database (DNHSPD) has kept information on all prescriptions for reimbursed drugs dispensed by community pharmacies in Denmark since 2004 according to Anatomical Therapeutic Chemical (ATC) classification system (ATC codes). Data from the DNHSPD can account for patient's medication.…”

Section: Data Sourcesmentioning

confidence: 99%

Risk factors for new chronic opioid use after hip fracture surgery: a Danish nationwide cohort study from 2005 to 2016 using the Danish multidisciplinary hip fracture registry

et al. 2021

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ObjectiveTo examine the risk factors for new chronic opioid use in elderly patients who underwent hip fracture surgery.DesignProspective population-based cohort study.Setting and participantsUsing Danish nationwide health registries, we identified all opioid non-user patients aged ≥65 years who had undergone hip fracture surgery from 2005 to 2016 and were alive within the first year following surgery.Main outcome measuresNew chronic opioid use defined by the dispensing of at least two prescription opioids within two of the last three quarters during the first year following surgery.ResultsWe identified 37 202 opioid non-user patients who underwent hip fracture surgery. Of these, 5497 (15%) developed new chronic opioid user within 1 year of surgery. Risk factors for new chronic opioid use were Body Mass Index (BMI) of <18.5 (adjusted OR (aOR) 1.22, 95% CI 1.09 to 1.36), BMI of 25.0–29.9 (aOR 1.12, 95% CI 1.04 to 1.21) and BMI of ≥30 (aOR 1.57, 95% CI 1.40 to 1.76) with BMI 18.6–24.9 as reference, a pertrochanteric/subtrochanteric fracture (aOR 1.27, 95% CI 1.20 to 1.34) with femoral neck fracture as reference, preoperative use (vs no-use) of non-steroidal anti-inflammatory drug (aOR 1.68, 95% CI 1.55 to 1.83), selective serotonin reuptake inhibitor (aOR 1.42, 95% CI 1.32 to 1.53), antidepressants (aOR 1.36, 95% CI 1.24 to 1.49), antipsychotics (aOR 1.21, 95% CI 1.07 to 1.35), corticosteroids (aOR 1.54, 95% CI 1.35 to 1.76), statins (aOR 1.09, 95% CI 1.02 to 1.18), antibiotics (aOR 1.32, 95% CI 1.22 to 1.42), antiosteoporosis drugs (aOR 1.33, 95% CI 1.19 to 1.49) and anticoagulatives (aOR 1.24, 95% CI 1.17 to 1.32). Presence of cardiovascular comorbidities, diabetes, gastrointestinal diseases, dementia, chronic obstructive pulmonary disease or renal diseases was further identified as a risk factor.ConclusionIn this large nationwide cohort study, we identified several risk factors associated with new chronic opioid use after hip fracture surgery among patients who were alive within the first year following surgery. Although not all factors are modifiable preoperative, this will allow clinicians to appropriately counsel patients preoperatively and tailor postoperative treatment.

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“…The PPV of the diagnosis trochanteric fracture was 92% and of subtrochanteric fracture 83%, ie, results that are comparable to our numbers. 7 …”

Section: Discussionmentioning

confidence: 99%

<p>Diagnosis of Open Tibial Fracture Showed High Positive Predictive Value in the Swedish National Patient Register</p>

Tampe¹,

Frank²,

Weiss³

et al. 2020

CLEP

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Introduction: The Swedish National Patient Register was validated only for a few diagnoses in the field of trauma. In this study, we calculated the positive predictive values (PPV) of the diagnosis of open tibial fracture and corresponding E-codes (cause of injury). Patients and Methods: Out of 2845 cases from a 10-year period (2007-2016), a random sample of 300 cases was selected for review of medical records. The accuracy of the diagnosis and cause of injury was calculated and presented as PPV. We divided the study population into two subgroups (moderate and severe injury) that were analyzed separately. Severe injury was defined as when a patient had an amputation and/or reconstructive surgical procedures, indicated by corresponding ICD-codes. Results: The PPV of the diagnosis of open tibial fracture was 87% (95% CI: 86-88%) overall, 86% (95% CI: 79-91%) for moderate injuries and 96% (95% CI: 91-98%) for severe injuries. The PPV for E-codes was 74% (95% CI: 65-81%). The majority of injuries were caused by falls (47%) or transport accidents (38%). Most of these injuries were caused by high-energy trauma (60%). Conclusion: The PPV of the diagnosis of open tibial fracture in the Swedish National Patient Register is high (87%). The PPV of E-codes was lower (79%). The results imply that the register is well suited for healthcare evaluation and research purposes regarding trauma diagnoses. Most open tibial fractures are high-energy injuries.

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<p>The Positive Predictive Value of Hip Fracture Diagnoses and Surgical Procedure Codes in the Danish Multidisciplinary Hip Fracture Registry and the Danish National Patient Registry</p>

Cited by 37 publications

References 23 publications

Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Validity of Self-Reported Diagnosis of Osteoporosis in Japan Nurses’ Health Study

Risk factors for new chronic opioid use after hip fracture surgery: a Danish nationwide cohort study from 2005 to 2016 using the Danish multidisciplinary hip fracture registry

<p>Diagnosis of Open Tibial Fracture Showed High Positive Predictive Value in the Swedish National Patient Register</p>

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