&lt;p&gt;Magnetic Resonance Imaging (MRI) Phenotypes May Provide Additional Information for Risk Stratification for Encapsulated Papillary Carcinoma of the Breast&lt;/p&gt;

Tang, Wenjie; Liang, Yongquan; Yan, Jing; Hu, Yue; Sun, Meili; Guoshun, Liu; Xu, Pan; Wei, Xinhua; Jiang, Xinqing; Guo, Yuan

doi:10.2147/cmar.s277980

Cited by 4 publications

(3 citation statements)

References 18 publications

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“…Maric J et al ( 17 ) also reported that there were no significant correlations between malignant lesion subtypes and ADC values. The highest ADC value of malignant pathology in our study attributed to EPC was 1.15 × 10 -3 mm 2 /s, which did not correspond to the study of Tang WJ et al ( 18 ). The mean ADC value in his study was 0.876 × 10 -3 mm 2 /s based on 11 EPC lesions.…”

Section: Discussioncontrasting

confidence: 99%

Contribution of Diffusion-Weighted Imaging and ADC Values to Papillary Breast Lesions

Zheng

Guan

et al. 2022

Front. Oncol.

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This study aimed to evaluate the role of apparent diffusion coefficient (ADC) values obtained from diffusion-weighted imaging (DWI) in the differentiation of malignant from benign papillary breast lesions. The magnetic resonance imaging (MRI) data of 94 breast papillary lesions confirmed by pathology were retrospectively analyzed. The differences in ADC values of papillary lesions under different enhancements in MRI and different pathological types were investigated, and the ADC threshold was determined by the receiver operating characteristic curve for its potential diagnostic value. The mean ADC values in borderline and malignant lesions (1.01 ± 0.20 × 10-3 mm2/s) were significantly lower compared to benign lesions (1.21 ± 0.27 × 10-3 mm2/s) (P < 0.05). The optimal threshold of the ADC value could be 1.00 × 10-3 mm2/s. The ADC values were statistically significant in differentiating between benign and malignant papillary lesions whether in mass or non-mass enhancement (P < 0.05). However, there were no statistical differences in the ADC values among borderline or any other histological subtypes of malignant lesions (P > 0.05). Measuring ADC values from DWI can be used to identify benign and malignant breast papillary lesions. The diagnostic performance of the ADC value in identifying benign and malignant breast lesions is not affected by the way of lesion enhancement. However, it shows no use for differential diagnosis among malignant lesion subtypes for now. The ADC value of 1.00 × 10-3 mm2/s can be used as the most appropriate threshold for distinguishing between benign and malignant breast papillary lesions.

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Section: Discussioncontrasting

confidence: 99%

Contribution of Diffusion-Weighted Imaging and ADC Values to Papillary Breast Lesions

Zheng

Guan

et al. 2022

Front. Oncol.

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“…According to the characteristics of most series available in the literature, it is observed that the cases are advanced age, hormone positive, HER 2 (‐) and have a low Ki67 index. Moreover, the axillary involvement rate of the patients is generally below 10%, and there is no prognostic difference between the EPC‐in situ/EPC‐inv groups 10–15 . The median tumor size in the literature is reported as .3–9 cm, while it is 2.1 cm in ours.…”

Section: Discussionmentioning

confidence: 47%

“…Moreover, the axillary involvement rate of the patients is generally below 10%, and there is no prognostic difference between the EPC-in situ/EPC-inv groups. [10][11][12][13][14][15] The median tumor size in the literature is reported as .3-9 cm, while it is 2.1 cm in ours. Also, the incidence of invasive component in the literature varies between 13% and 57%, and the rate of axillary lymphatic involvement is 3%-11%, and these values were 31% and 6%, respectively, in our study.…”

Section: Rakha Et Al Analyzed the Papillary Neoplasm Data From Differentmentioning

confidence: 45%

Oncological outcomes for encapsulated papillary carcinoma of the breast: Multicentric study of Turkish Society for Radiation Oncology breast cancer study group (TROD 06–014 study)

GÜRDAL

Yıldırım

Gürsel

et al. 2022

Asia-Pac J Clncl Oncology

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BackgroundEncapsulated papillary carcinoma (EPC) is a rare malignant papillary breast cancer accounting for approximately .5%–2% of all breast tumors. The aim of this multicenter study was to evaluate clinicopathologic features of EPC in addition to oncological outcomes and radiotherapy (RT) details.MethodsFrom 10 different academic hospitals in Turkey, we obtained pathology reports of 80 patients with histologically confirmed EPC between 2005 and 2022. Demographic, diagnostic, and treatment data were collected from medical records, retrospectively. Local failure, distant progression, toxicity‐adverse effects, overall survival (OS), and disease‐free survival were evaluated, and survival analyzes were performed using the Kaplan–Meier method.ResultsEighty patients with the diagnosis of misspelled sorry (ECP) were retrospectively evaluated. The median age of the patients was 63 (range, 35–85). After a median follow‐up of 48 (range; 6–206) months, local recurrence was observed in three patients (4%). Local recurrence was less common in the patients who received whole breast RT with a tumour bed boost (p = .025). There were not any distant metastasis or disease‐related death. RT was applied to 61% of the cases, and no treatment‐related grade 3 or higher toxicity was reported in any of the patients. Five year OS, cancer‐specific survival (CSS), and were observed as 85%, 100%, and 96%, respectively.ConclusionsECP is a rare, slow‐progressing breast carcinoma associated with good prognosis, it is a disease of elderly patient, and usually occurs in postmenopausal women. It responds extremely well to optimal local treatments and appropriate adjuvant treatments on a patient basis, and has excellent OS and CSS ratios.

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Preoperative MRI of breast squamous cell carcinoma: diagnostic value of distinguishing between two subtypes

Chen

et al. 2022

Clinical Radiology

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<p>Magnetic Resonance Imaging (MRI) Phenotypes May Provide Additional Information for Risk Stratification for Encapsulated Papillary Carcinoma of the Breast</p>

Cited by 4 publications

References 18 publications

Contribution of Diffusion-Weighted Imaging and ADC Values to Papillary Breast Lesions

Contribution of Diffusion-Weighted Imaging and ADC Values to Papillary Breast Lesions

Oncological outcomes for encapsulated papillary carcinoma of the breast: Multicentric study of Turkish Society for Radiation Oncology breast cancer study group (TROD 06–014 study)

Preoperative MRI of breast squamous cell carcinoma: diagnostic value of distinguishing between two subtypes

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