&lt;p&gt;Khat Chewing and Type 2 Diabetes Mellitus&lt;/p&gt;

Badedi, Mohammed; Darraj, Hussain; Hummadi, Abdulrahman; Najmi, Abdullah; Solan, Yahiya; Zakry, Ibrahim; Khawaji, Abdullah; Zaylai, Sayedah; Rajeh, Norah; Alhafaf, Hassan Q.; Hakami, Wali; Bakkari, Awaji; Kriry, Maryam; Dagreri, Abdulraheem; Haddad, Ebrahim

doi:10.2147/dmso.s240680

Cited by 21 publications

(27 citation statements)

References 31 publications

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“…Similar results were found in previous studies conducted in Jazan. [30][31][32] It has been found that DM-related distress 18,19,22 and depression 18,22 have a negative impact on glycemic control. In psychological conditions such as DM distress and depression, regulatory hormones and neurotransmitters, such as catecholamine, glucocorticoids, growth hormones, and glucagon, are activated.…”

Section: Discussionmentioning

confidence: 99%

Diabetes-Related Distress and Depression in Saudis with Type 2 Diabetes

Alzughbi¹,

Badedi²,

Darraj³

et al. 2020

PRBM

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Objective: This study aims to assess the prevalence of diabetes mellitus (DM)-related distress and depression and their associated factors in Saudi people with type 2 DM (T2DM) in Jazan, Saudi Arabia. It also aims to assess the association between glycemic control and DM-related distress and depression. Methods: This is an analytical, cross-sectional study which recruited 300 Saudi patients with T2DM randomly from primary healthcare centers in Jazan, Saudi Arabia. DM-related distress and depression were measured by valid questionnaires, the 17-item Diabetes Distress Scale and the Patient Health Questionnaire-9, respectively. Logistic regression and an independent t-test were performed in the statistical analysis. Results: The mean age of the study population was 52.7 years, with a range of 23-83 years. The number of males was 147 (49%) and females was 153 (51%) in the study population. The prevalence of DM-related distress and depression in Saudi patients with T2DM in Jazan was 22.3% and 20%, respectively, and about 7.7% had both. Of DM-related distress, 12.3% had interpersonal-related DM distress, 11.7% had physician-related DM distress, 10.7% had emotional-related DM distress, and 7% had regimen-related DM distress. After adjusting for covariates, being female, patients aged <45, physical inactivity, DM duration <5 years, and smoking were significantly associated with DM-related distress and depression. There was also a significant association between DM-related distress and depression, OR = 3 [95% CI: 1.8, 6.4]. Furthermore, we found that glycated hemoglobin (A1C) levels were significantly higher in those with DM-related distress (small effect size, eta squared = 0.04) and depression (moderate effect size, eta squared = 0.06) (P < 0.001). Conclusion: DM-related distress and depression are prevalent in patients with T2DM in Jazan, Saudi Arabia. Both these conditions need to be screened for and addressed in clinical settings. Establishing the causality of DM-related distress and depression in T2DM is an important aim for any future studies.

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Section: Discussionmentioning

confidence: 99%

Diabetes-Related Distress and Depression in Saudis with Type 2 Diabetes

Alzughbi¹,

Badedi²,

Darraj³

et al. 2020

PRBM

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“…50 The findings related to khat consumption are consistent with studies in countries where khat consumption is common; Khat chewers' had an increased risk of developing MetS than those who did not chew. 48,49 Moreover, evidence shows in Yemen khat chewing was positively associated with the level of dyslipidemia compared to non-chewers. 50 The findings related to sedentary behavior are also consistent with previous studies in working adults.…”

Section: Discussionmentioning

confidence: 99%

Metabolic Syndrome Among Working Adults in Eastern Ethiopia

Motuma¹,

Gobena²,

Roba³

et al. 2020

DMSO

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Purpose Metabolic syndrome (MetS) has become a public health challenge in low-income countries due to changing lifestyle and the food environment. However, studies on the prevalence of metabolic syndrome and associated factors are limited in Ethiopia. Therefore, this study assessed the prevalence of MetS and its associated factors among working adults in eastern Ethiopia. Methods A cross-sectional study was conducted involving 1,164 working adults from December 2018 to February 2019. Data were collected following the World Health Organization (WHO) STEPwise approach. The data collection tools include a structured questionnaire, anthropometric, and biochemical measurements. Prevalence was calculated using International Diabetes Federation criteria. A Poisson regression model with robust variance estimation was used to investigate the independent variable’s association with MetS. An adjusted prevalence ratio with 95% confidence interval was reported to show associations. Results The prevalence of MetS was 20.1% (95% CI=17.8–22.4) among the participants. It was more prevalent among females (APR:=1.62, 95% CI=1.31–2.00), those of 35–44 years of age (APR:=3.14, 95% CI=1.19–8.28), 45–54 years of age (APR=4.42, 95% CI=1.66–11.77), and 55–64 years of age (APR=6.03, 95% CI=2.27–16.06), khat chewers (APR=1.30, 95% CI=1.06–1.60), those with 8 or more hours of sedentary behavior (APR=2.29, 95% CI=1.88–2.80), and those consuming alcohol 5–6 days per week (APR=1.81, 95% CI=1.20–2.74). The prevalence was significantly lower in those eating five or more fruits and vegetables servings per day (APR=0.04, 95% CI=0.01–0.27). Conclusion A high prevalence of MetS was observed among working adults in eastern Ethiopia. Strengthening workplace health promotion programs is necessary to reduce the negative consequences of MetS in workplaces and protect productivity.

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“…This case–control study was conducted on Saudi patients with COVID-19 in Jazan Region, located in southwestern Saudi Arabia and characterized by a relatively homogenous population with similar ethnic and socioeconomic characteristics [ [10] , [11] , [12] , [13] , [14] ].…”

Section: Methodsmentioning

confidence: 99%