&lt;p&gt;Endomyocardial Fibrosis: Diagnosis and Management&lt;/p&gt;

Khalil, Siddiq Ibrahim

doi:10.2147/jvd.s196348

Cited by 8 publications

(14 citation statements)

References 40 publications

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“…Even in non-tropical regions, the diagnosis of EMF should always be considered in restrictive cardiomyopathy. Cardiac MRI has a definitive role in confirming and characterising EMF and is better than echocardiography for delineating the extent of cavity obliteration and the presence of intracardiac thrombi 5…”

Section: Discussionmentioning

confidence: 99%

Intracardiac mass revealing a rare form of cardiomyopathy

et al. 2022

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We present the case of a woman with a 2-month history of exertional dyspnoea and fatigue in which echocardiography revealed a cavity-obliterating right ventricular mass. Further imaging evaluation using cardiac magnetic resonance showed a thrombotic mass as well as diffuse myocardial oedema and endomyocardial fibrosis (EMF) that involved both ventricles. In the absence of any other cause (including peripheral eosinophilia), the diagnosis of idiopathic EMF was established. This case highlights this uncommon disease in non-tropical areas.

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Section: Discussionmentioning

confidence: 99%

Intracardiac mass revealing a rare form of cardiomyopathy

et al. 2022

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“…It is characterized mainly by fibrosis of the apical endocardium, mainly in the right, left, or both ventricles. The clinical manifestations usually arise from the symptoms of heart failure secondary to restrictive LV filling 2 . The symptoms depend on the extent of involvement of the ventricles.…”

Section: Discussionmentioning

confidence: 99%

“…The leading cause of it is still unknown. However, there are multiple theories available regarding its development 2 . Treatment is challenging as currently there are limited data; medical therapy as a case of restrictive heart failure might offer symptomatic relief.…”

Section: Introductionmentioning

confidence: 99%

Endomyocardial fibrosis in a non‐tropical patient who presented with chest pain mimicking ACS and left ventricular thrombus, case report

matarneh

Hailan

Karim

et al. 2022

Clinical Case Reports

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Endomyocardial fibrosis (EMF) is a disease known to cause restrictive cardiomyopathy. It shows a high prevalence in tropical countries. Several triggering factors have been proposed. However, the pathogenesis is still a mystery. The disease is progressive, and the outcome is generally unfavorable. The most common symptom is heart failure. However, an atypical presentation may be expected. Our case presented with symptoms suggestive of ischemia and missed diagnosis initially as ischemic cardiomyopathy. This report aims to increase the attention and awareness of this disease. We present a case of a 53‐year‐old man referred to the emergency department for sudden chest pain, left‐sided and non‐radiating lasted for several minutes, awoke him from sleep with no associated symptoms. He is known to have Diabetes type‐2 and hypertension on oral therapy. Cardiac markers were within the normal limit. The patient was discharged home with an appointment at the cardiology outpatient clinic. Echocardiography was done and revealed mildly reduced left ventricular (LV) systolic function, Ejection Fraction of 46%, asymmetric LV hypertrophy affecting the apical segments with aneurysm, and calcified apical thrombus. CT coronary angiography was done with non‐significant Left Anterior Descending artery lesions and left ventricular hypertrophy affecting the apex with calcified apical thrombus. Further investigation by cardiac MRI revealed apical thrombus and late apical uptake suggesting Endomyocardial Fibrosis of possible eosinophilic etiology. The patient continued to have attacks of similar chest pain, for which stress cardiac MRI was done and was negative for ischemia. Another diagnostic workup was done, including hematological and serological tests such as Antinuclear Antibodies and Schistosoma Antibodies. The patient was kept on valsartan and Bisoprolol with oral anticoagulant (vitamin K antagonist) and Rosuvastatin. EMF may have a heterogeneous presentation and should be considered in a patient with calcific apical thrombus without previous history of cardiac problem, even in the non‐tropical region.

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“…it is characterized mainly by fibrosis of the apical endocardium mainly in the right, left or both ventricles. The clinical manifestations of it usually arise from the symptoms of heart failure secondary to restrictive LV filling (2). The symptoms depend on the extent of involvement of the ventricles.…”

Section: Case Presentationmentioning

confidence: 99%

“…It is prevalent in tropical and subtropical parts of the world. The main cause of it is still unknown, however, there are multiple theories available regarding its development (2). Treatment is challenging as currently there is limited data, medical therapy as a case of restrictive heart failure might offer a symptomatic relief, however the disease is usually progressive, and the long-term outcome is generally poor.…”

Section: Introductionmentioning

confidence: 99%