In patients who underwent PCI, polypharmacy at discharge could play a negative role in the adherence to the first refill of EBM. Further studies should investigate other parameters that contribute to long term non-adherence.
Background: Cardiac manifestations of COVID-19 are associated with a significant increase in morbidity and mortality.
Objective: To study outcome of patients having cardiovascular manifestations of COVID-19 infection.
Materials and Methods: The study was conducted at Hazem Mebaireek General Hospital, Qatar from March 8th to August 30th, 2020. 467 patients admitted with COVID-19 and cardiac manifestations were retrospectively studied. Patients of both genders, age >18 years with cardiac manifestations were studied. Data was collected by chart reviews on Cerner.
Results: Mean age of the study population was 55.12±14.87 years, 438(93.8%) males and 29(6.2%) females. Hypertension was observed in 251(53.7%) and diabetes mellitus in 238(51%) patients. Reason for cardiology consultation was raised Troponins in 77(16.5%), abnormal ECG in 75(16.1%) and chest pain in 66(14.1%) patients. Cardiac diagnosis was Myocardial injury in 108(23.1%) and Type II MI in 72(15.4%), STEMI in 51(10.9%), and NSTEMI in 51(10.9%) patients. Atrial fibrillation was observed in 76(16.3%). The mean hospital stay was 15.4±23.5 days. For STEMI primary PCI was performed in 28(54.9%), thrombolysis administered in 11(21.5%), and 12(23.5%) patients were treated medically. Overall mortality was 67(14.3%), with in-hospital mortality of 66(14.1%) and 1(0.2%) patient died post-discharge. CRP level was significantly higher in deceased patients, p-value <0.00001.
Conclusion: Abnormal ECG, chest pain, Myocardial injury, Type II MI, ST, and Non-ST elevation MI were common cardiovascular manifestations in COVID pneumonia. Raised CRP, Trop T, Urea, creatinine, and WBC counts were predictors of in-hospital death in COVID patients.
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