&lt;p&gt;A Novel Approach to Treatment of Conjunctival Cyst Ablation Using Atmospheric Low-Temperature Plasma&lt;/p&gt;

Nejat, Farhad; Jadidi, Khosrow; Pirhadi, Shiva; Adnani, Seyede-Yasamin; Nabavi, Nazanin-Sadat; Nejat, Mohammad Amin

doi:10.2147/opth.s265032

Cited by 25 publications

(33 citation statements)

References 25 publications

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“…With one-day, one-week, and oneto six-month follow-up, this study has demonstrated that patients' cysts have completely healed and no recurrence observed. (11) Using this method in punctal occlusion seems to be a temporary practical approach for treating dry eye disease. (13) In pinguecula treatment, the study showed that (PANIS method) is effective, and after six months of follow-up, no recurrence and complications were observed.…”

Section: Resultsmentioning

confidence: 99%

“…(8, 9) Also, the effectiveness of the PANIS method in treating Conjunctivochalasis, Dry eye disease, Pinguecula and Conjunctival Cyst has been shown in human studies. (10)(11)(12)(13) In this study, for the rst time, we intend to use this method to treat patients with conjunctival concretions and examine its possible side effects as a new method.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treatment of Conjunctival Concretions; A Clinical Case Series

Nejat

Jadidi²,

Eghtedari³

et al. 2021

Preprint

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Purpose: Plasma is one of the newest therapies recently used in Conjunctivochalasis, Conjunctival Cyst, and Blepharoplasty. This study aimed to evaluate a quick treatment modality of conjunctival concretions using plasma as a noninvasive procedure.Design: Six eyes of six patients with conjunctival concretions were evaluated in a clinical case series.Methods: The procedure was performed using plasma spots generated by the white handpiece of the Plexr device. The eyelid was everted and concretions sublimated by plasma spots from the upper and lower eyelids. Refractive Errors, visual acuity (BCVA and UCVA), Ocular Surface Disease Index (OSDI), and Intraocular pressure (IOP) were measured before and after six months of the procedure.Results: The results of 6 months follow-up show that this effective method had no recurrence or side effects. Treatment was effective in all of the patients. No complication and recurrence was observed. The OSDI score was improved to the normal range. This method had no effects on Refractive Errors, Visual Acuity, and IOP. Conclusions: Based on the results, it seems that the PANIS method can be used as a practical, quick, and straightforward approach for the treatment of conjunctival concretions.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treatment of Conjunctival Concretions; A Clinical Case Series

Nejat

Jadidi²,

Eghtedari³

et al. 2021

Preprint

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“…Also, a new approach to treating conjunctival cysts using ALTP has been introduced by Nejat et al [ 22 ]. They used the Plexr device for removing cysts ranged from 2.1 to 4.8 mm.…”

Section: Discussionmentioning

confidence: 99%

Safety evaluation of the atmospheric low-temperature plasma (ALTP) on the conjunctiva: an animal study and histopathological findings; 6-month follow-up

et al. 2021

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Background Plasma medicine is an innovative research field focused on the application of atmospheric-pressure low-temperature plasmas (ALTP) for therapeutic purposes. Considering the potentials of plasma in ophthalmology, in this study, we evaluated the safety of plasma on the conjunctival tissue in animal models for 6 months. Methods Twelve adult male New Zealand albino rabbits were divided into four groups. The right eye of each rabbit was chosen for the test and the left eye was considered as the control. Experiments were performed using the Plexr device (GMV, Rocca Priora, RM, Italy). Four plasma spots were applied on the superior part of the conjunctiva (from 10 to 2 o’clock positions) using the continuous mode and a low power level (white handpiece) of the Plexr. For evaluation of the plasma safety, the histopathological changes were assessed 1 week (A), 1 month (B), 3 months (C), and 6 months (D) after the intervention. Results According to the histopathological findings, a mild decrease in blood vessels and severe stromal edema, as well as a superficial epithelium loss, were observed in group A. No chronic inflammation, scar tissue, deposition, and hemorrhage were found in group B. Epithelialization was confirmed by the histological examinations after 1 month. There was no evidence of atypia or dysplasia after 3 and 6 months. Conclusion In conclusion, there were no persistent histopathological changes on conjunctival tissue after plasma exposure. Then, plasma can be considered as a minimally invasive alternative method for treating some ocular surface disorders.

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“…In ocular surface disorders, plasma-assisted noninvasive surgery (PANIS) has been used for Conjunctival cyst and conjunctivochalasis treatment so far. According to the results of these studies, the PANIS method is effective, safe, rapid, and affordable with a short recovery time [16,17] .…”

Section: Introductionmentioning

confidence: 97%

Evaluation of Plasma-Assisted Noninvasive Surgery (PANIS) As a New Approach for Pterygium Removal with Amniotic Membrane Transplantation (AMT); a Clinical Case Series

Nejat

Jadidi

Eghtedari

et al. 2021

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Purpose: Medical plasma application has been used in different fields recently. In this study, we assess the outcome of using plasma-assisted noninvasive surgery (PANIS) with amniotic membrane transplantation (AMT) in pterygium surgical treatment. Methods: This clinical case series was conducted in 4 patients with primary grades 1, 2, and 3 pterygium (Table 1). After exclusion and inclusion criteria considerations, patients underwent different examinations. Various measurements were obtained such as uncorrected visual acuity (UCVA), refractive error (RE), the best-corrected visual acuity (BCVA), and ocular surface disease index (OSDI). The surgical procedure was pterygium removal from the cornea and then AMT attached to the conjunctival borders with plasma spots using a white handpiece of Plexr device (Plexr, GMV s.r.l Grottaferrata, Italy) instead (Table 2). After postoperative follow-ups within the first week of the surgery and in 1 month and 6 months later the results were obtained. Results: All patients have been fully recovered after the surgery without any complications. In all 4 cases, UCVA, BCVA, and RE parameters have improved during 6 months after the surgical procedure. Every patients’ OSDI decreased after the surgery. Recurrence has not been seen in any cases during 6 months follow-up. Conclusion: Pterygium removal surgery using the PANIS technique with AMT is safe, effective, fast, and cost-benefit.

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<p>A Novel Approach to Treatment of Conjunctival Cyst Ablation Using Atmospheric Low-Temperature Plasma</p>

Cited by 25 publications

References 25 publications

Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treatment of Conjunctival Concretions; A Clinical Case Series

Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treatment of Conjunctival Concretions; A Clinical Case Series

Safety evaluation of the atmospheric low-temperature plasma (ALTP) on the conjunctiva: an animal study and histopathological findings; 6-month follow-up

Evaluation of Plasma-Assisted Noninvasive Surgery (PANIS) As a New Approach for Pterygium Removal with Amniotic Membrane Transplantation (AMT); a Clinical Case Series

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