Evaluation of Plasma Assisted Noninvasive Surgery (PANIS) as a New Approach for the Treatment of Conjunctival Concretions; A Clinical Case Series

Abstract

Purpose: Plasma is one of the newest therapies recently used in Conjunctivochalasis, Conjunctival Cyst, and Blepharoplasty. This study aimed to evaluate a quick treatment modality of conjunctival concretions using plasma as a noninvasive procedure.Design: Six eyes of six patients with conjunctival concretions were evaluated in a clinical case series.Methods: The procedure was performed using plasma spots generated by the white handpiece of the Plexr device. The eyelid was everted and concretions sublimated by plasma spots from the upper and lower eyelids. Refractive Errors, visual acuity (BCVA and UCVA), Ocular Surface Disease Index (OSDI), and Intraocular pressure (IOP) were measured before and after six months of the procedure.Results: The results of 6 months follow-up show that this effective method had no recurrence or side effects. Treatment was effective in all of the patients. No complication and recurrence was observed. The OSDI score was improved to the normal range. This method had no effects on Refractive Errors, Visual Acuity, and IOP. Conclusions: Based on the results, it seems that the PANIS method can be used as a practical, quick, and straightforward approach for the treatment of conjunctival concretions.

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“…In these studies, the safety of the plasma on the rabbits' cornea, limbus, and conjunctiva was evaluated and followed up one month and six months after the intervention. According to these studies, plasma can be considered as a novel technique for treating some ocular surface disorders such as Conjunctivochalasis, Dry eye disease, Pinguecula, pterygium, Conjunctival Concretions, and Conjunctival Cyst [10][11][12][13][14]. In all studies no complications were seen during and after treatment.…”

“…Vision parameters has not been change in all three patients, although they have not much potential vision. Despite of the novelty of this method, researchers have recently shown that it can be a suitable replacement for some treatments [12,22] (11,22). Nevertheless, the present study is a case study, and a clinical trial is needed to compare this method with other treatments.…”

“…A new method that has been recently considered as a treatment in ophthalmology, called PANIS (Plasma assisted noninvasive surgery) using plasma as the fourth state of matter to treat Conjunctivochalasis, Dry eye disease, Pinguecula, pterygium, Conjunctival Concretions, and Conjunctival Cyst [10][11][12][13][14]. Plasma technology is effective even in Wound healing, infection control, and cancer treatment [15].…”