<p>A Comparative Prevalence Of Metabolic Syndrome Among Type 2 Diabetes Mellitus Patients In Hawassa University Comprehensive Specialized Hospital Using Four Different Diagnostic Criteria</p>

Abstract

BackgroundRecognition of MetS in type two diabetic patients is important in starting the appropriate preventive and therapeutic measures. The commonly used definitions of MetS have similarities and discrepancies. Different definitions defined metabolic syndrome differently. IDF, WHO, NCEP-ATP III, and the harmonized definitions were used frequently to determine the prevalence of metabolic syndrome.ObjectivesThis study was aimed to investigate the prevalence of MetS and its associated factors among patients with type 2 Diabetes Mellitus using four definitions and to identify the concordance and the difference of these four definitions.MethodsA cross-sectional study was conducted from February 28 to May 30/2017 at Hawassa university comprehensive specialized hospital. The study involved 314 study participants selected by simple random sampling technique. Logistic regression was used to determine associated factors of metabolic syndrome, and kappa statistics was used to determine the concordance between different definitions of metabolic syndrome. In any cases, a p-value of <0.05 was considered to be statistically significant.ResultThe prevalence of metabolic syndrome according to IDF, WHO, harmonized, and NCEP-ATP III diagnostic criteria was 59.9%, 31.2%, 65.6%, and 70.1%, respectively. Our study found the maximum agreement between IDF and NCEP criteria (K=0.54, P<0.001) and IDF and Harmonized(K=0.65, P<0.001). Uric acid level was associated factor of metabolic syndrome by all the four definitions, and total cholesterol was associated factors by the three definitions.ConclusionThe prevalence of metabolic syndrome varies based on the definition used and the highest prevalence of MetS was observed with NCEP-ATP III and the different types of criteria do not always diagnose the same group of individuals.

Metabolic syndrome and lifestyle factors among type 2 diabetes mellitus patients in Dessie Referral Hospital, Amhara region, Ethiopia

“…The odds of MetS among females was 2.43 times more likely than males. It was similar with studies conducted in urban India, Sub-Saharan Africa, and Ethiopia [ 9 , 10 , 16 , 23 ]. This might be because of physiological factors like menopause-related hormonal changes might lead females to metabolic impairment [ 12 ].…”

“…In this study, the odds of MetS was increased with age which was supported by most studies [ 9 , 26 , 30 , 31 ]. It is known that the level of physical activity decreases with increased age.…”

“…Whereas it was lower than studies from Urban India (71.9%), and Kumasi, Ghana (90.6%) [ 23 , 24 ]. It was also lower than studies conducted in Hawassa, South Ethiopia (70.1%), and Gonder, North-west Ethiopia (66.7%) by the same definition of MetS [ 9 , 10 ]. This might be due to the differences in the level of hospital, and population characteristics.…”

“…Based on a systematic review in Sub-Saharan Africa, the prevalence of MetS among T2DM patients was 59.62% [ 8 ]. In Ethiopia, the prevalence of MetS among T2DM patients reached up to 70.1% with different diagnostic criteria of MetS [ 9 – 11 ].…”

Comparative study on prevalence of metabolic syndrome based on three criteria among adults in Zhejiang province, China: an observational study

“…The concordance between IDF 2005 and harmonising criteria 2009 based on their greater similarity was further supported by a study from Ethiopia. 44 The difference of their kappa coefficients by sex was due to the WC criterion that it is identical in females but different in males. From our findings, using harmonising criteria 2009 is likely to improve identification of highrisk cardiometabolic factors in Chinese populations for early intervention of MetS.…”