“…There is no relationship between anisocytosis and MCV, as variation in the size of RBCs may occur for all values of MCV [ 18 ]. Tomita et al [ 20 ] reported that a 2-year dietary treatment with p,p ’-DDT resulted in microcytic anemia in rats as supported by significant decreases in HCT, HGB, RBC, MCV, and MCH after 12-weeks of treatment and significant decreases in HCT, HGB, MCV, and MCH after 26, 52, and 78 weeks of treatment. As shown in Table 2 (male) and Table 3 (female), there were no statistically significant changes reported in rats in either RBC or HGB at any of the doses tested, as well as in MCV or MCHC, supporting that the changes in MCH and RDW alone are not indicative of anemia or of toxicological significance in this study.…”