Safe long-term therapy of Cushing’s syndrome over 37 years with mitotane
Jonas Seibold,
Mario Hönemann,
Anke Tönjes
et al.
Abstract:While suggested, surgery is not always possible as a first-line treatment of Cushing’s Disease (CD). In such cases, patients require medical therapy in order to prevent complications resulting from hypercortisolism. Although there has been a wide expansion in pharmacological options in recent years, mitotane was the agent of choice for treating hypercortisolism decades ago. Due to the introduction of other therapies, long-term experience with mitotane remains limited. Here, we report the case of a woman with C… Show more
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