&lt;i&gt;In vitro&lt;/i&gt; phytochemical and antimicrobial screening of &lt;i&gt;Thymus linearis&lt;/i&gt;

Naz, Attiqa; Saeed, Muhammad; Hussain, Muhammad Medrar; Ishaq, Muhammad

doi:10.3329/bjp.v10i1.20639

Cited by 17 publications

(9 citation statements)

References 16 publications

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“…Pant and Samant (2010) reported that whole plant of Thymus linearis is given to women during labor and postnatal period. The plant is reported to possess some important secondary metabolites including terpenoids, flavonoids, tannins, alkaloids and glycosides (Naz et al 2015) and has anti-inflammatory, antipyretic, hepatoprotective, and antibacterial activities (Ahmad et al 2014;Naz et al 2015). In the current study root decoction of Geranium wallichianum is used to relieve labor pain.…”

Section: %mentioning

confidence: 82%

Medicinal plants used during Pregnancy and Childbirth in Baramulla District of Jammu and Kashmir, India

Jan

Khare

Mir

2021

Ethnobot. Res. App.

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Background: Although medicinal plants have long been beneficial to women's health, understanding regarding their usage during pregnancy and childbirth is scarce. This is the first research of its kind in the study area, with the aim of documenting and preserving traditional knowledge of medicinal plants used during pregnancy and childbirth.Materials and methods: Field surveys were carried out from August 2018 to December 2020 in Baramulla district of Jammu and Kashmir. Information was gathered through group discussions, field tours and personal interviews using standard questionnaire with the tribal people, traditional healers, midwives and pregnant women. The data collected was analyzed through Use value (UV) and Informant Consensus factor (ICF).Results: A total of 60 medicinal plant species belonging to 56 genera and 30 families were reported to be commonly utilized by women for treating various health issues during pregnancy and childbirth. The Lamiaceae was found to be the most prevalent plant family, with leaves being the most regularly used plant part. Of all other methods of remedy preparation decoction was reported to be the most preferred. Childbirth had the highest ICF value and the most widely accepted medicinal plants were Cydonia oblonga, Malva neglecta, Thymus linearis, Geranium wallichianum, Achyranthes aspera, Taraxacum officinale and Ajuga bracteosa as per the Use Value. Conclusion:The current findings highlight the need for more in-depth research into the phytochemical, pharmacological, and toxicological aspects of commonly used medicinal plants for pregnancy and childbirth related health issues in order to provide reliable information to primary users and to develop novel drugs.

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Section: %mentioning

confidence: 82%

Medicinal plants used during Pregnancy and Childbirth in Baramulla District of Jammu and Kashmir, India

Jan

Khare

Mir

2021

Ethnobot. Res. App.

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“…Asparagus racemosus (Asparagaceae) is commonly called as 'Kurilo'; traditionally used to cure stomach problems and skin diseases [24] and have antihepatotoxic, antineoplastic, antiprotozoal, adaptogenic, antiulcer, antioxidant, antilithiatic, antidepressant, anti-inflammatory, and cytotoxicity activities [25]. Thymus linearis (Lamiaceae) is commonly called as 'Ghodamarcha'; traditionally used to cure stomach problems, cough, cold, and eye infection [26] and have antihypertensive [27], anti-inflammatory, antipyretic [28], hepatoprotective [29], antioxidant, anticholinergic [30], and antimicrobial [31] activities. Pleurospermum benthamii (Apiaceae) is commonly called as 'Gandhaina' and used to cure Diarrhea, dysentery, constipation, gastritis, cough, cold, headache, and indigestion [2].…”

Section: Introductionmentioning

confidence: 99%

In-vitro antioxidant, anti-cancer, and anti-inflammatory activities of selected medicinal plants from western Nepal

et al. 2020

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Background This study was focused on the measurement of anticancer properties of six medicinal plants from western Nepal in three cell lines; HeLa, Hep3B, and HCT116, and anti-inflammatory properties in RAW 264.7 cell line through NO, PGE2, and TNF-α production. In addition, the phytochemical screening, total phenolic, flavonoid content, and antioxidant properties were evaluated. Results The qualitative phytochemical analysis revealed the presence of different secondary metabolite and range of total phenolic and total flavonoid content. The highest antioxidant activities were observed in Bergenia pacumbis against both DPPH (IC50 = 25.97 ± 0.19 μg/mL) and ABTS (IC50 = 14.49 ± 0.40 μg/mL). Furthermore, the highest antiproliferative effect against cervical, liver, and colon cancer cell lines were observed in Melia azedarach as IC50 values of 10.50, 5.30, and 1.57 μg/mL respectively, while the strongest anti-metastatic potential on liver cancer cell line was found in Pleurospermum benthamii. In addition, P. benthamii showed the most potent anti-inflammatory effect in RAW264.7 murine macrophage cells. Conclusion This study provided the evidence for M. azedarach and P. benthamii to have great anticancer potential and finding builds the enough scientific backgrounds in future to isolate and purify the bioactive compounds for further applications.

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“…Phytochemical analysis of crude extract of plant showed presence of flavonoids, sterols, steroids and triterpenoids. These essential oils have already been reported to have analgesic, anti-inflammatory and antipyretic activities by inhibition of COX enzyme by a mechanism same like non-steroidal anti-inflammatory drugs [18,19]. Therefore, the analgesic, antiinflammatory and antipyretic activities of Thymus linearis may be due to these compounds.…”

Section: Discussionmentioning

confidence: 98%

In Vivo Biological Investigation of Methanolic Extract of Thymus linearis Whole Plant

Naz¹,

Saeed²,

Ghaffar³

et al. 2018

Am J Ethnomed

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Background and purpose: For treatment of pain, pyrexia and inflammation, medicinal plants have exhibited enormous capability. Medicinal plants are used as anti-pyretic, analgesic and anti-inflammatory agents having low gastro intestinal tract disturbing adverse effects. In order to tackle and assure the antipyretic, analgesic and anti-inflammatory response of herbs, scientific backdrop is mandatory.Experimental approach: Abdominal writhing was introduced to experimental mice by intra peritoneal injection (i.p) of 1% acetic acid. Pain is induced thermally by observance the mice on hotplate having temperature around 50°C. For antipyretic activity, pyrexia was induced by 20 ml/kg body weight (b.w) i.p brewer's yeast injection. Anti-inflammatory activity was examined in mice by Carrageenan. Thymus linearis methanolic extract (TLME) was used at test doses of 100, 200 and 300 mg/kg b. w i.p in mice.Key results: TLME showed reduced writhing in acetic acid method with dose of 100, 200 and 300 mg/kg b. w by 54.00 ± 1.15, 44.00 ± 1.15 and 32.66 ± 0.66 in comparison of control i.e. 66.66 ± 1.76. The latency times in hotplate method was significantly increased from 13.95% to 21.22% at dose of 100 to 300 mg/kg. Antipyretic effect of TLME exhibited 39.70 ± 0.01 protections at 300 mg/kg after 2 h as similar to standard drug Paracetamol 38.57 ± 0.06. Anti-inflammatory effect of TLME was significantly observed by 36.66% and 35.29% respectively at dose of 300 mg/kg. Conclusion and implications:Results of TLME showed that it can be used to treat pyrexia, pain and inflammation. This investigation actively reinforced the ethno pharmacological uses of T. linearis as analgesic, antipyretic and anti-inflammatory agent.

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<i>In vitro</i> phytochemical and antimicrobial screening of <i>Thymus linearis</i>

Cited by 17 publications

References 16 publications

Medicinal plants used during Pregnancy and Childbirth in Baramulla District of Jammu and Kashmir, India

Medicinal plants used during Pregnancy and Childbirth in Baramulla District of Jammu and Kashmir, India

In-vitro antioxidant, anti-cancer, and anti-inflammatory activities of selected medicinal plants from western Nepal

In Vivo Biological Investigation of Methanolic Extract of Thymus linearis Whole Plant

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