<i>In Vitro</i> Bioactivity and Physical-Mechanical Properties of HA Based 45S5 Bio-Composites

Abstract

Bio-glass® and hydroxyapatite (Ca10 (PO4)6(OH) 2, HA) has been widely used as a bone replacement material in restorative dental and orthopedic implants. In order to analyze in vitro bioactivity bio-composite before and after exposed to simulated body fluid (SBF) solution for different time periods were investigated by fourier transform infrared (FTIR) reflectance spectrometer with measuring the pH and concentration of silicon, sodium, calcium, phosphorus and manganese ions in SBF solution. The prepared bio-composites were assessed by XRD, FTIR, mechanical properties. FTIR confirmed the presence of a rich bone like apatite layer post-immersion on the composite surface. It has been found that the new BG/HA bio-composite materials have high bioactivity properties. These bio-composite materials are promising for medical applications such as bone substitutes.

Preparation and physical‐biological characterization on titanium doped fluorophosphate nanobioglass: Bone implants

“…implants is assessed by their elastic properties. 18 The variation profile of Young's and shear moduli (48.02-50.67 Gpa and 18.29-18.82 Gpa ) of the materials reflected the variation in the density profile.…”